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  4. TRNAU1AP Antibody

TRNAU1AP Antibody

  • 中文名稱：
    TRNAU1AP兔多克隆抗體
  • 貨號：
    CSB-PA025008GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    TRNAU1AP
  • 別名：
    1110007F05Rik antibody; AA387999 antibody; FLJ20503 antibody; PRO1902 antibody; RP4 669K10.4 antibody; SECp43 antibody; tRNA selenocysteine 1-associated protein 1 antibody; tRNA selenocysteine associated protein 1 antibody; tRNA selenocysteine-associated protein 1 antibody; Trnau1ap antibody; TRSPAP1 antibody; TSAP1_HUMAN antibody; WI1 2643G14.2 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human TRNAU1AP,SECP43
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能：
    Involved in the early steps of selenocysteine biosynthesis and tRNA(Sec) charging to the later steps resulting in the cotranslational incorporation of selenocysteine into selenoproteins. Stabilizes the SECISBP2, EEFSEC and tRNA(Sec) complex. May be involved in the methylation of tRNA(Sec). Enhances efficiency of selenoproteins synthesis.
  • 基因功能參考文獻(xiàn)：
    1. Knockdown of Trnau1ap reduced cell migration and proliferation. Knockdown of Trnau1ap blocked the PI3K/Akt signaling pathway. PMID: 29758194
    2. Data confirm interactions among components of the early steps of the selenocysteine biosynthesis pathway (SEPSECS, SECP43, SEPHS1, and SEPHS2); SECP43, which interacts with SEPSECS and SEPHS1, is a globular protein that forms oligomers in vivo. PMID: 28414460
    3. our studies delineating the multiple, coordinated protein-nucleic acid interactions between SECp43 and the selenoprotein cotranslational factors. PMID: 16508009
  • 亞細(xì)胞定位：
    Nucleus. Cytoplasm.
  • 蛋白家族：
    RRM TRSPAP family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 30813

    KEGG: hsa:54952

    STRING: 9606.ENSP00000362936

    UniGene: Hs.533626