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  4. TTYH1 Antibody, FITC conjugated

TTYH1 Antibody, FITC conjugated

  • 中文名稱：
    TTYH1兔多克隆抗體, FITC偶聯(lián)
  • 貨號：
    CSB-PA867139LC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) TTYH1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    TTYH1
  • 別名：
    TTYH1; Protein tweety homolog 1; hTTY1
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Protein tweety homolog 1 protein (50-178AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Probable chloride channel. May be involved in cell adhesion.; Isoform 3 may be a Ca(2+)-independent and swelling-activated chloride channel, possibly involved in regulation of cell volume.
  • 基因功能參考文獻：
    1. In this report, we identify tweety-homolog 1 (Ttyh1), a membrane protein linked to neuronal development, as a potent driver of tumor microtube (TM)-mediated brain colonization by glioma cells. PMID: 28607172
    2. TTYH1 was not expressed in either the malignant or the control samples PMID: 25182704
    3. Fusion of TTYH1 with the C19MC microRNA cluster drives expression of a brain-specific DNMT3B isoform in the embryonal brain tumor. PMID: 24316981
    4. Nedd4-2 differentially interacts with and regulates TTYH1-3 PMID: 18577513
  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Tweety family
  • 組織特異性：
    Expressed in brain, eye, ovary and testis, and at lower levels in muscle, placenta, liver and lung.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 13476

    OMIM: 605784

    KEGG: hsa:57348

    UniGene: Hs.268728