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  4. Thrsp Antibody, Biotin conjugated

Thrsp Antibody, Biotin conjugated

  • 中文名稱：
    Thrsp兔多克隆抗體, Biotin偶聯(lián)
  • 貨號(hào)：
    CSB-PA726789HD01MO
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Mus musculus (Mouse) Thrsp Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    Thrsp
  • 別名：
    Thrsp antibody; S14 antibody; Thyroid hormone-inducible hepatic protein antibody; Spot 14 protein antibody; S14 antibody; SPOT14 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Mouse
  • 免疫原：
    Recombinant Mouse Thyroid hormone-inducible hepatic protein (1-150AA)
  • 免疫原種屬：
    Mus musculus (Mouse)
  • 標(biāo)記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Plays a role in the regulation of lipogenesis, especially in lactating mammary gland. Important for the biosynthesis of triglycerides with medium-length fatty acid chains. May modulate lipogenesis by interacting with MID1IP1 and preventing its interaction with ACACA. May function as transcriptional coactivator. May modulate the transcription factor activity of THRB.
  • 基因功能參考文獻(xiàn)：
    1. These findings implicate Spot14 as a direct protein enhancer of FASN catalysis in the mammary gland during lactation when maximal MCFA production is needed. PMID: 24771867
    2. S14 has a potential role in regulating mammary tumor growth and fatty acid synthesis in vivo. Modulating the amount of medium chain fatty acids, by changing the levels of S14, has the potential to impact malignant mammary tumor phenotypes. PMID: 25472762
    3. Data indicate SPOT14 as a potent marker for adult NSPCs that react dynamically to positive and negative neurogenic regulators. PMID: 25418721
    4. The structure of S14 suggests a mechanism whereby heterodimer formation with MIG12 attenuates the ability of MIG12 to activate ACC. PMID: 20952656
    5. Spot 14 protein, absent in the lactating mammary gland, is required for maximum efficiency of de novo lipid synthesis in vivo PMID: 15890771
    6. the daily rhythm of Spot14 expression in the liver is under the control of the light-entrainable oscillator, food-entrainable oscillator, and food-derived nutrients, in a separate or cooperative manner PMID: 17660449
    7. the S14-R protein is a compensatory factor, at least partially responsible for the normal liver lipogenesis observed in the S14 null mouse PMID: 18556348

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  • 亞細(xì)胞定位：
    Nucleus. Cytoplasm.
  • 蛋白家族：
    SPOT14 family
  • 組織特異性：
    Mainly expressed in tissues that synthesize triglycerides.
  • 數(shù)據(jù)庫鏈接：