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  4. UBE2Z Antibody

UBE2Z Antibody

  • 中文名稱：
    UBE2Z兔多克隆抗體
  • 貨號：
    CSB-PA875692ESR2HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: UBE2Z antibody at 3.37µg/ml
      Lane 1: MCF-7 whole cell lysate
      Lane 2: HepG2 whole cell lysate
      Lane 3: Hela whole cell lysate
      Lane 4: Mouse gonadal tissue
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 39, 29 kDa
      Observed band size: 39 kDa
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA875692ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA875692ESR2HU at dilution of 1:100
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) UBE2Z Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    FLJ13855 antibody; GC17P044341 antibody; HOYS7 antibody; Uba6 specific E2 conjugating enzyme 1 antibody; UBA6 specific enzyme E2 antibody; Uba6-specific E2 conjugating enzyme 1 antibody; UBE2Z antibody; UBE2Z_HUMAN antibody; Ubiquitin carrier protein Z antibody; Ubiquitin conjugating enzyme E2 Z antibody; Ubiquitin conjugating enzyme E2Z antibody; Ubiquitin protein ligase Z antibody; Ubiquitin-conjugating enzyme E2 Z antibody; Ubiquitin-protein ligase Z antibody; Use1 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human, Mouse
  • 免疫原：
    Recombinant Human Ubiquitin-conjugating enzyme E2 Z protein (115-354AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Catalyzes the covalent attachment of ubiquitin to other proteins. Specific substrate for UBA6, not charged with ubiquitin by UBE1. May be involved in apoptosis regulation.
  • 基因功能參考文獻(xiàn)：
    1. The SNP rs46522 in UBE2Z gene is associated with the risk of coronary Artery disease in the individuals of Chinese Han descent with type 2 diabetes and is of synergistic effect with Body mass index. PMID: 28840129
    2. we found that USE1 proteins were frequently overexpressed in human lung cancer. Furthermore, overexpression of USE1 promoted in vivo and in vitro proliferation, migration, and invasion. PMID: 28376205
    3. Association of UBE2Z single nucleotide polymorphism rs46522 with the susceptibility to coronary artery disease in an Iranian population. PMID: 26602883
    4. UBE2Z was widely expressed in human tissues and is located on chromosome 17q21. PMID: 17160626
    5. In tissue culture cells, Uba6 is required for charging a previously uncharacterized Uba6-specific E2 (Use1), whereas Ube1 is required for charging the cell-cycle E2s Cdc34A and Cdc34B PMID: 17597759

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  • 亞細(xì)胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    Ubiquitin-conjugating enzyme family
  • 組織特異性：
    Widely expressed. Highly in placenta, pancreas, spleen and testis.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 25847

    OMIM: 611362

    KEGG: hsa:65264

    STRING: 9606.ENSP00000354201

    UniGene: Hs.514297