UBXN4 Antibody

說明書

產(chǎn)品詳情

Uniprot No.：

Q92575
基因名：

UBXN4
別名：

UBXN4 antibody; KIAA0242 antibody; UBXD2 antibody; UBXDC1 antibody; UBX domain-containing protein 4 antibody; Erasin antibody; UBX domain-containing protein 2 antibody
宿主：

Rabbit
反應(yīng)種屬：

Human,Mouse,Rat
免疫原：

Human UBXN4
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA,WB,IF
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunofluorescence (IF) Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Involved in endoplasmic reticulum-associated protein degradation (ERAD). Acts as a platform to recruit both UBQLN1 and VCP to the ER during ERAD.
基因功能參考文獻(xiàn)：
1. Erasin/UBXD2 may be involved in endoplasmic-reticulum-associated protein degradation and in Alzheimer's disease. PMID: 16968747
2. Knockdown of erasin, a platform for p97/VCP and ubiquilin binding, or knockdown of ubiquilin in human cells slowed degradation of two classical endoplasmic reticulum-associated protein degradation substrates. PMID: 19822669
亞細(xì)胞定位：

Endoplasmic reticulum membrane; Peripheral membrane protein. Nucleus envelope.
組織特異性：

Expressed in many tissues, including heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Accumulates in Alzheimer disease-afflicted brains (at protein level).
數(shù)據(jù)庫鏈接：

HGNC: 14860

OMIM: 611216

KEGG: hsa:23190

STRING: 9606.ENSP00000272638

UniGene: Hs.591242