UGP2 Antibody

說明書

產(chǎn)品詳情

產(chǎn)品名稱：

Rabbit anti-Homo sapiens (Human) UGP2 Polyclonal antibody
Uniprot No.：

Q16851
基因名：

UGP2
別名：

pHC379 antibody; UDP glucose diphosphorylase antibody; UDP glucose pyrophosphorylase 1 antibody; UDP glucose pyrophosphorylase 2 antibody; UDP glucose pyrophosphorylase antibody; UDP-glucose pyrophosphorylase antibody; UDPG antibody; UDPGP 2 antibody; UDPGP antibody; UDPGP2 antibody; UGP 1 antibody; UGP 2 antibody; UGP1 antibody; Ugp2 antibody; UGPA_HUMAN antibody; UGPase 2 antibody; UGPase antibody; UGPP 1 antibody; UGPP 2 antibody; UGPP1 antibody; UGPP2 antibody; Uridyl diphosphate glucose pyrophosphorylase 1 antibody; Uridyl diphosphate glucose pyrophosphorylase 2 antibody; UTP glucose 1 phosphate uridyltransferase antibody; UTP glucose 1 phosphate uridylyltransferase 2 antibody; UTP glucose 1 phosphate uridylyltransferase antibody; UTP--glucose-1-phosphate uridylyltransferase antibody
宿主：

Rabbit
反應(yīng)種屬：

Human, Mouse
免疫原：

Recombinant Human UTP--glucose-1-phosphate uridylyltransferase protein (1-497AA)
免疫原種屬：

Homo sapiens (Human)

標(biāo)記方式：

Non-conjugated

本頁面中的產(chǎn)品，UGP2 Antibody (CSB-PA620986HA01HU)，的標(biāo)記方式是Non-conjugated。對于UGP2 Antibody，我們還提供其他標(biāo)記。見下表：

標(biāo)記方式	貨號	產(chǎn)品名稱	應(yīng)用
HRP	CSB-PA620986HB01HU	UGP2 Antibody, HRP conjugated	ELISA
FITC	CSB-PA620986HC01HU	UGP2 Antibody, FITC conjugated
Biotin	CSB-PA620986HD01HU	UGP2 Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA, WB, IHC

推薦稀釋比：

Application	Recommended Dilution
WB	1:1000-1:5000
IHC	1:20-1:200

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen.
基因功能參考文獻(xiàn)：
1. High UGP2 expression is associated with malignant pancreatic lesions. PMID: 29347944
2. This study provides clear evidence that the octameric state is a prerequisite for activity in the uridine diphosphate-glucose pyrophosphorylase. PMID: 23254995
3. The crystal structure was determined and shown to form octamers through end-to-end and side-by-side interactions. Mutagenesis studies showed that both dissociation of octamers and mutations of the latch loop can significantly affect the activity. PMID: 22132858
4. GYS1 regulation by HIF plays a central role in the hypoxic accumulation of glycogen, and hypoxia also upregulates the expression of UTP:glucose-1-phosphate urydylyltransferase (UGP2) and 1,4-alpha glucan branching enzyme (GBE1) PMID: 20300197
亞細(xì)胞定位：

Cytoplasm.
蛋白家族：

UDPGP type 1 family
組織特異性：

Highly expressed in various brain regions. Expressed in amygdala, anterior cingulate cortex, caudate, cerebellar hemisphere, cerebellum, cortex, frontal cortex, hippocampus, hypothalamus, nucleus accumbens, putamen, spinal cord and substantia nigra. Also
數(shù)據(jù)庫鏈接：

HGNC: 12527

OMIM: 191750

KEGG: hsa:7360

STRING: 9606.ENSP00000338703

UniGene: Hs.516217