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  4. UQCR10 Antibody

UQCR10 Antibody

  • 中文名稱：
    UQCR10兔多克隆抗體
  • 貨號：
    CSB-PA890670ESR1HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human heart tissue using CSB-PA890670ESR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA890670ESR1HU at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) UQCR10 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    UQCR10 antibody; UCRC antibody; HSPC119 antibody; Cytochrome b-c1 complex subunit 9 antibody; Complex III subunit 9 antibody; Complex III subunit X antibody; Cytochrome c1 non-heme 7 kDa protein antibody; Ubiquinol-cytochrome c reductase complex 7.2 kDa protein antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Cytochrome b-c1 complex subunit 9 protein (1-63AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
  • 基因功能參考文獻：
    1. Reciprocal fusion gene involving UQCR10 and C1orf194 is associated with spinal ependymoma. PMID: 27401149
    2. Functionality of complex III of the mitochondrial electron transport chain is required for the hypoxic stabilization of HIF-1 alpha and HIF-2 alpha PMID: 16054089
  • 亞細胞定位：
    Mitochondrion inner membrane; Single-pass membrane protein.
  • 蛋白家族：
    UQCR10/QCR9 family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 30863

    OMIM: 610843

    KEGG: hsa:29796

    STRING: 9606.ENSP00000332887

    UniGene: Hs.284292