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UQCRQ Antibody

  • 中文名稱：
    UQCRQ兔多克隆抗體
  • 貨號：
    CSB-PA03855A0Rb
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: UQCRQ antibody at 2µg/ml
      Lane 1: EC109 whole cell lysate
      Lane 2: 293T whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/15000 dilution
      Predicted band size: 10 kDa
      Observed band size: 30 kDa
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) UQCRQ Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    Complex III subunit 8 antibody; Complex III subunit VIII antibody; Cytochrome b-c1 complex subunit 8 antibody; QCR8 antibody; QCR8_HUMAN antibody; QP-C antibody; QPC antibody; Ubiquinol-cytochrome c reductase complex 9.5 kDa protein antibody; Ubiquinol-cytochrome c reductase complex ubiquinone-binding protein QP-C antibody; Uqcrq antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Cytochrome b-c1 complex subunit 8 protein (2-78AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，UQCRQ Antibody (CSB-PA03855A0Rb)，的標(biāo)記方式是Non-conjugated。對于UQCRQ Antibody，我們還提供其他標(biāo)記。見下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA03855B0Rb UQCRQ Antibody, HRP conjugated ELISA
    FITC CSB-PA03855C0Rb UQCRQ Antibody, FITC conjugated
    Biotin CSB-PA03855D0Rb UQCRQ Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c.
  • 基因功能參考文獻(xiàn)：
    1. QP-C protein gene expression involved in the development of hyperpigmentation. PMID: 25950827
    2. Decreased electron Transport Complex III activity is associated with ulcerative colitis. PMID: 20440543
    3. We thus suggest that a homozygous mutation in UQCRQ is associated with defective function of mitochondrial complex III, leading to a severe autosomal-recessive neurological phenotype. PMID: 18439546
  • 相關(guān)疾病：
    Mitochondrial complex III deficiency, nuclear 4 (MC3DN4)
  • 亞細(xì)胞定位：
    Mitochondrion inner membrane; Single-pass membrane protein.
  • 蛋白家族：
    UQCRQ/QCR8 family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 29594

    OMIM: 612080

    KEGG: hsa:27089

    STRING: 9606.ENSP00000367934

    UniGene: Hs.146602