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VWA5A Antibody

  • 中文名稱：
    VWA5A兔多克隆抗體
  • 貨號(hào)：
    CSB-PA545063
  • 規(guī)格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA545063(VWA5A Antibody) at dilution 1/80, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA545063(VWA5A Antibody) at dilution 1/80, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    VWA5A
  • 別名：
    VWA5A antibody; BCSC1 antibody; LOH11CR2A antibody; von Willebrand factor A domain-containing protein 5A antibody; Breast cancer suppressor candidate 1 antibody; BCSC-1 antibody; Loss of heterozygosity 11 chromosomal region 2 gene A protein antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Fusion protein of Human VWA5A
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:10000
    IHC 1:100-1:300
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    May play a role in tumorigenesis as a tumor suppressor. Altered expression of this protein and disruption of the molecular pathway it is involved in, may contribute directly to or modify tumorigenesis.
  • 基因功能參考文獻(xiàn)：
    1. BCSC-1 binds to Sox10, which down regulates MITF, and results in a switch of melanoma cells from a proliferative to a migratory phenotype. PMID: 22594792
    2. LOH11CR2A, PIG8 and CHEK1 are candidate tumor suppressor genes associated with breast carcinoma and have significant clinical as well as prognostic importance. PMID: 21803008
    3. BCSC-1 suppression might play roles in tumorigenesis of some nasopharyngeal carcinomas PMID: 19656157
  • 組織特異性：
    Expressed at low level in many tissues. Not expressed in 80% of tumor cell lines tested.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 6658

    OMIM: 602929

    KEGG: hsa:4013

    STRING: 9606.ENSP00000376504

    UniGene: Hs.152944