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  4. YY1AP1 Antibody

YY1AP1 Antibody

  • 中文名稱：
    YY1AP1兔多克隆抗體
  • 貨號：
    CSB-PA026298GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    YY1AP1
  • 別名：
    FLJ10875 antibody; FLJ13914 antibody; GRNG antibody; HCCA1 antibody; HCCA2 antibody; Hepatocellular carcinoma susceptibility protein antibody; Hepatocellular carcinoma-associated protein 2 antibody; OTTHUMP00000033475 antibody; OTTHUMP00000033476 antibody; OTTHUMP00000200831 antibody; OTTHUMP00000200832 antibody; OTTHUMP00000200833 antibody; OTTHUMP00000200836 antibody; YAP antibody; YY1-associated protein 1 antibody; YY1AP antibody; YY1AP1 antibody; YYAP1_HUMAN antibody
  • 反應種屬：
    Human
  • 免疫原：
    Human YY1AP1
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20oC, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,IF
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Associates with the INO80 chromatin remodeling complex, which is responsible for transcriptional regulation, DNA repair, and replication. Enhances transcription activation by YY1. Plays a role in cell cycle regulation.
  • 基因功能參考文獻：
    1. Data indicate WW-binding protein 2 (WBP2) as an important co-factor of YY1 associated protein 1 (YAP) that enhances YAP/TEAD-mediated gene transcription. PMID: 28332498
    2. Loss-of-Function Mutations in YY1AP1 Lead to Grange Syndrome and a Fibromuscular Dysplasia-Like Vascular Disease. PMID: 27939641
    3. YY1AP1 may serve as a key molecular target for EpCAM(+) AFP(+) HCC subtype PMID: 25597408
    4. human liver cancer associated gene PMID: 11856496
    5. YY1AP is a novel co-activator of YY1 PMID: 14744866
    6. HCCA2 may play a novel role in cell cycle regulation. PMID: 17541814

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  • 相關疾病：
    Grange syndrome (GRNG)
  • 亞細胞定位：
    Cytoplasm. Nucleus. Nucleus, nucleoplasm. Nucleus, nucleolus.
  • 組織特異性：
    Ubiquitous. Detected in small intestine, skeletal muscle, lung, pancreas, brain, stomach, spleen, colon and heart. Detected at very low levels in healthy liver. Highly expressed in most liver carcinomas.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 30935

    OMIM: 602531

    KEGG: hsa:55249

    STRING: 9606.ENSP00000357323

    UniGene: Hs.584927