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ZBTB8OS Antibody, FITC conjugated

  • 中文名稱:
    ZBTB8OS兔多克隆抗體, FITC偶聯(lián)
  • 貨號:
    CSB-PA816894LC01HU
  • 規(guī)格:
    ¥880
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) ZBTB8OS Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    ZBTB8OS
  • 別名:
    ARCH antibody; ARCH_HUMAN antibody; ARCH2 antibody; Archease (ARCH) antibody; Archease like protein antibody; MGC62007 antibody; OTTHUMP00000036124 antibody; Protein archease antibody; Protein ZBTB8OS antibody; ZBTB8OS antibody; Zinc finger and BTB domain containing 8 opposite strand antibody; Zinc finger and BTB domain containing opposite strand protein 8 antibody; Zinc finger and BTB domain-containing opposite strand protein 8 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Protein archease protein (2-136AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    Component of the tRNA-splicing ligase complex required to facilitate the enzymatic turnover of catalytic subunit RTCB. Together with DDX1, acts by facilitating the guanylylation of RTCB, a key intermediate step in tRNA ligation.
  • 基因功能參考文獻:
    1. ARCH mutation is associated with chronic myelomonocytic leukemia. PMID: 26648538
    2. RTCB, the catalytic subunit of the tRNA ligase complex, and its co-factor archease mediate XBP1 mRNA splicing both in vitro and in vivo. PMID: 25378478
    3. archease (also called ZBTB8OS), a protein of unknown function, is required for full activity of the human tRNA ligase complex and, in cooperation with DDX1, facilitates the formation of an RTCB-guanylate intermediate central to mammalian RNA ligation PMID: 24870230
  • 蛋白家族:
    Archease family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 24094

    KEGG: hsa:339487

    STRING: 9606.ENSP00000417677

    UniGene: Hs.655921