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ZG16 Antibody, Biotin conjugated

  • 中文名稱：
    ZG16兔多克隆抗體, Biotin偶聯(lián)
  • 貨號(hào)：
    CSB-PA528909LD01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) ZG16 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    ZG16
  • 別名：
    hZG16 antibody; Jacalin like lectin domain containing antibody; JCLN antibody; JCLN1 antibody; Secretory lectin ZG16 antibody; Zg16 antibody; ZG16_HUMAN antibody; ZG16A antibody; Zymogen granule membrane protein 16 antibody; Zymogen granule protein 16 antibody; Zymogen granule protein 16 homolog antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Zymogen granule membrane protein 16 protein (17-167AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    May play a role in protein trafficking. May act as a linker molecule between the submembranous matrix on the luminal side of zymogen granule membrane (ZGM) and aggregated secretory proteins during granule formation in the TGN.
  • 基因功能參考文獻(xiàn)：
    1. our study demonstrated that ZG16 expression was sequentially reduced from normal, adenoma, to carcinoma. Association with multiple clinicopathological features indicates that ZG16 may play an important role in cancer initiation and progression. ZG16 may serve as a potential biomarker for diagnosis and prognosis of colorectal cancer PMID: 29661177
    2. Data show that an upstream regulator of zymogen granule protein 16 (ZG16), miR-196a, which was significantly overexpressed in colorectal cancer (CRC) and promotes cell growth and stemness. PMID: 27880730
    3. Pathogen-related glycan microarray analysis identified phosphatidylinositol mono- and di-mannosides (PIM1 and PIM2) as novel ligand candidates of ZG16p. PMID: 25919894
    4. Human ZG16p recognizes pathogenic fungi through non-self polyvalent mannose in the digestive system. PMID: 21893569
    5. the sugar-binding site and the adjacent basic patch of ZG16p and ZG16b cooperatively form a functional glycosaminoglycan-binding site. PMID: 21110947
    6. hZG16 was markedly down-regulated in hepatocellular carcinoma (HCC) as indicated by RT-PCR. PMID: 17307141

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  • 亞細(xì)胞定位：
    Secreted, extracellular space, extracellular matrix. Zymogen granule lumen. Golgi apparatus lumen.
  • 蛋白家族：
    Jacalin lectin family
  • 組織特異性：
    Highly expressed in liver. Detected at lower levels in colon, ileum and jejunum.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 30961

    KEGG: hsa:653808

    STRING: 9606.ENSP00000383563

    UniGene: Hs.632195