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ZIC5 Antibody, Biotin conjugated

  • 中文名稱(chēng)：
    ZIC5兔多克隆抗體, Biotin偶聯(lián)
  • 貨號(hào)：
    CSB-PA850433LD01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng)：
    Rabbit anti-Homo sapiens (Human) ZIC5 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    ZIC5
  • 別名：
    zic5 antibody; ZIC5_HUMAN antibody; Zinc finger protein of the cerebellum 5 antibody; Zinc finger protein ZIC 5 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Zinc finger protein ZIC 5 protein (217-276AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Biotin
  • 克隆類(lèi)型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Essential for neural crest development, converting cells from an epidermal fate to a neural crest cell fate. Binds to DNA.
  • 基因功能參考文獻(xiàn)：
    1. hsa_circ_0007534 serves as an oncogene in glioma via promoting ZIC5 expression by repressing miR-761 availability. PMID: 29605301
    2. ZIC5 positively regulated the proliferation, migration, and survival of prostate colorectal cancer cells PMID: 29024195
    3. ZIC5 is highly upregulated in non-small cell lung cancer tumor tissues and may act as an oncogene by influencing CCNB1 and CDK1 complex expression PMID: 27663664
    4. ZIC1, ZIC2, and ZIC5 may have roles in meningiomas PMID: 20199689
    5. the smallest 13q deletion associated to DWM allows further narrowing of the previously established critical region for this brain malformation to 13q32.2-32.3. Among the few genes of the deleted region, ZIC2 and ZIC5 seem the most plausible candidates. PMID: 20683983

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  • 亞細(xì)胞定位：
    Nucleus.
  • 蛋白家族：
    GLI C2H2-type zinc-finger protein family
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 20322

    OMIM: 617896

    KEGG: hsa:85416

    STRING: 9606.ENSP00000267294

    UniGene: Hs.508570