ZNF638 Antibody

產(chǎn)品詳情

Uniprot No.：

Q14966
基因名：

ZNF638
別名：

CTCL tumor antigen se33 1 antibody; CTCL-associated antigen se33-1 antibody; Cutaneous T cell lymphoma associated antigen se33 1 antibody; Cutaneous T-cell lymphoma-associated antigen se33-1 antibody; DKFZp686P1231 antibody; MGC26130 antibody; MGC90196 antibody; NP220 antibody; NP220 nuclear protein antibody; Nuclear protein 220 antibody; ZFML antibody; Zfp638 antibody; Zinc finger matrin like antibody; Zinc finger matrin like protein antibody; Zinc finger matrin-like protein antibody; Zinc finger protein 638 antibody; ZN638_HUMAN antibody; ZNF 638 antibody; Znf638 antibody
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Synthesized peptide derived from the Internal region of Human NP220.
免疫原種屬：

Homo sapiens (Human)
標(biāo)記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

WB, IHC, ELISA

推薦稀釋比：

Protocols：

Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
ELISA Protocol
儲(chǔ)存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Transcription factor that binds to cytidine clusters in double-stranded DNA. Plays a key role in the silencing of unintegrated retroviral DNA: some part of the retroviral DNA formed immediately after infection remains unintegrated in the host genome and is transcriptionally repressed. Mediates transcriptional repression of unintegrated viral DNA by specifically binding to the cytidine clusters of retroviral DNA and mediating the recruitment of chromatin silencers, such as the HUSH complex, SETDB1 and the histone deacetylases HDAC1 and HDAC4. Acts as an early regulator of adipogenesis by acting as a transcription cofactor of CEBPs (CEBPA, CEBPD and/or CEBPG), controlling the expression of PPARG and probably of other proadipogenic genes, such as SREBF1. May also regulate alternative splicing of target genes during adipogenesis.
基因功能參考文獻(xiàn)：
1. ZNF638 is a novel and early regulator of adipogenesis that works as a transcription cofactor of C/EBPs. PMID: 21602272
亞細(xì)胞定位：

Nucleus speckle.
數(shù)據(jù)庫(kù)鏈接：

HGNC: 17894

OMIM: 614349

KEGG: hsa:27332

STRING: 9606.ENSP00000264447

UniGene: Hs.434401