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  4. lktA Antibody
  • 中文名稱：
    lktA兔多克隆抗體
  • 貨號：
    CSB-PA314743EA01ESE
  • 規(guī)格：
    ￥440
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品描述：

    CUSABIO produced the polyclonal antibody against lktA by immunizing rabbits with a synthetic peptide that corresponds to amino acids 715-953 of the recombinant Leukotoxin protein. The antiserum obtained from the rabbits was purified using protein G affinity chromatography, resulting in a purity level of 95% for the anti-lktA antibody.

    This antibody is an unconjugated IgG that specifically reacts with Escherichia coli lktA. LktA is a virulence factor generated by the bacterium Mannheimia haemolytica, which targets and kills immune cells, particularly leukocytes, in the lungs of infected animals. The lktA polyclonal antibody developed by CUSABIO is suitable for detecting the lktA protein in ELISA.

  • 產(chǎn)品名稱：
    Rabbit anti-Mannheimia haemolytica lktA Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    lktA
  • 別名：
    lktA antibody; Leukotoxin antibody; Lkt antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Mannheimia haemolytica
  • 免疫原：
    Recombinant Mannheimia haemolytica Leukotoxin protein (715-953AA)
  • 免疫原種屬：
    Mannheimia haemolytica
  • 標記方式：
    Non-conjugated

    本頁面中的產(chǎn)品，lktA Antibody (CSB-PA314743EA01ESE)，的標記方式是Non-conjugated。對于lktA Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA314743EB01ESE lktA Antibody, HRP conjugated ELISA
    FITC CSB-PA314743EC01ESE lktA Antibody, FITC conjugated
    Biotin CSB-PA314743ED01ESE lktA Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Pasteurella leukotoxins are exotoxins that attack host leukocytes and especially polymorphonuclear cells, by causing cell rupture. The leukotoxin binds to the host LFA-1 integrin and induces a signaling cascade leading to many biological effects, including tyrosine phosphorylation of the CD18 tail, elevation of the intracellular Ca(2+) and lysis of the host cell. This leukotoxin is a major contributor to the pathogenesis of lung injury in ovine pneumonic pasteurellosis. It has also weak hemolytic activity.
  • 亞細胞定位：
    Secreted. Host cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    RTX prokaryotic toxin (TC 1.C.11) family