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  4. oprF Antibody, Biotin conjugated

oprF Antibody, Biotin conjugated

Rare Species
  • 中文名稱：
    oprF兔多克隆抗體, Biotin偶聯(lián)
  • 貨號：
    CSB-PA318417LD01EZX
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Pseudomonas aeruginosa oprF Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    oprF
  • 別名：
    oprF antibody; PA1777 antibody; Outer membrane porin F antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Pseudomonas aeruginosa
  • 免疫原：
    Recombinant Pseudomonas aeruginosa Outer membrane porin F protein (25-350AA)
  • 免疫原種屬：
    Pseudomonas aeruginosa
  • 標(biāo)記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Has porin activity, forming small water-filled channels. Also has a structural role in determining cell shape and ability to grow in low-osmolarity medium.
  • 基因功能參考文獻(xiàn)：
    1. OprF (an outer membrane porin, highly conserved in the Pseudomonas) binds human C3b. PMID: 25964476
    2. LecB binds to the outer membrane protein OprF PMID: 23056489
    3. oprF transcription was increased in response to low NaCl or high sucrose concentrations, and this induced transcription was strongly impaired in the absence of SigX. PMID: 22685281
    4. Prevention of disulfide bond formation in OprF increases its pore-forming activity. PMID: 20978537
    5. This is the first study showing a link between OprF, PQS synthesis, T3SS, and virulence factor production PMID: 21189321
    6. Data show that the recombinant plasmid pIRES-tPA-OprF-MyD88 has been successfully constructed and tPA-OprF and MyD88 protein can be highly expressed in transfected cells. PMID: 19257978
    7. findings suggest that OprF could adopt two alternative conformations in the outer membrane and that folding is thermoregulated PMID: 15528532
    8. findings demonstrate that interferon-gamma binds to an outer membrane protein in Pseudomonas aeruginosa, OprF, resulting in the expression of a quorum-sensing dependent virulence determinant, the PA-I lectin PMID: 16051797
    9. analysis of OprF from Pseudomonas aeruginosa PMID: 16397890
    10. OprF exists in two different conformations PMID: 16595653
    11. analysis of Pseudomonas aeruginosa porin OprF PMID: 16617058
    12. Major outer membrane protein F (OprF) is identified as a protein with important functions; mutant Pseudomonas aeruginosa deficient in OprF negates the antibacterial role of host neutrophil elastase both in vitro and in a pneumonia model. PMID: 18802098

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  • 亞細(xì)胞定位：
    Cell outer membrane; Multi-pass membrane protein.
  • 蛋白家族：
    OmpA family
  • 數(shù)據(jù)庫鏈接：

    KEGG: pae:PA1777

    STRING: 208964.PA1777