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  4. prfA Antibody
  • 中文名稱：
    prfA兔多克隆抗體
  • 貨號(hào)：
    CSB-PA325257XA01LPY
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western Blot
      Positive WB detected in Recombinant protein
      All lanes: prfA antibody at 1:2000
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 31.4 kDa
      Observed band size: 30 kDa
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    prfA
  • 別名：
    Listeriolysin regulatory protein, prfA
  • 反應(yīng)種屬：
    Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)
  • 免疫原：
    Recombinant Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) Listeriolysin regulatory protein (1-237aa)
  • 免疫原種屬：
    Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Protein G
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Positively regulates expression of listeriolysin, of 1-phosphadidylinositol phosphodiesterase (PI-PLC) and other virulence factors.
  • 基因功能參考文獻(xiàn)：
    1. Spontaneous loss of virulence in natural populations of Listeria monocytogenes due to mutations in hlyA and PrfA has been demonstrated. PMID: 28827366
    2. PepP peptidase plays a role in posttranslational activation of the major virulence regulator, PrfA. PepP mediates recruitment of PrfA to the cytoplasmic membrane. PMID: 28396325
    3. The truncated C-terminus of prfA considerably contributes to the strongly attenuated phenotype observed in vitro. PMID: 25813546
    4. A novel bile exclusion locus bilE, coordinately regulated by sigmaB and PrfA, represents a new and important virulence factor in L. monocytogenes. PMID: 15686563
    5. PrfA K220T amino acid substituted mutant gene in an EGDDeltaprfA strain did not restore the haemolytic and phosphatidylcholine phospholipase C activities, in contrast to the wild-type prfA gene. PMID: 17379709

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  • 數(shù)據(jù)庫(kù)鏈接：

    KEGG: lmo:lmo0200

    STRING: 169963.lmo0200