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中文名稱:ptxA兔多克隆抗體, FITC偶聯
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貨號:CSB-PA356423LC01Bua
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規(guī)格:¥880
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其他:
產品詳情
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產品名稱:Rabbit anti-Bordetella pertussis ptxA Polyclonal antibody
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Uniprot No.:
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基因名:ptxA
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別名:ptxA antibody; BP3783 antibody; Pertussis toxin subunit 1 antibody; PTX S1 antibody; Islet-activating protein S1 antibody; IAP S1 antibody; NAD-dependent ADP-ribosyltransferase antibody; EC 2.4.2.- antibody
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宿主:Rabbit
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反應種屬:Bordetella pertussis
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免疫原:Recombinant Bordetella pertussis Pertussis toxin subunit 1 protein (35-269AA)
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免疫原種屬:Bordetella pertussis
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標記方式:FITC
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克隆類型:Polyclonal
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抗體亞型:IgG
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純化方式:>95%, Protein G purified
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濃度:It differs from different batches. Please contact us to confirm it.
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保存緩沖液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產品提供形式:Liquid
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儲存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途:For Research Use Only. Not for use in diagnostic or therapeutic procedures.
相關產品
靶點詳情
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功能:S1 is an NAD-dependent ADP-ribosyltransferase, which plays a crucial role in the pathogenesis of B.pertussis causing disruption of normal host cellular regulation. It catalyzes the ADP-ribosylation of a cysteine in the alpha subunit of host heterotrimeric G proteins. In the absence of G proteins it also catalyzes the cleavage of NAD(+) into ADP-ribose and nicotinamide. It irreversibly uncouples the G-alpha GTP-binding proteins from their membrane receptors.
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基因功能參考文獻:
- It has been proposed that it is the systemic activity of pertussis toxin and not pulmonary pathology that promotes mortality in critical pertussis. PMID: 28784932
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亞細胞定位:Secreted. Note=The individual chains are secreted by a sec-dependent mechanism into the periplasm. Then, S1 associates with the outer membrane before it joins with the B subunit to form the secretion-competent holotoxin. The type IV secretion system ptl mediates secretion of assembled toxin through the outer membrane.
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蛋白家族:Bacterial exotoxin subunit A family
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數據庫鏈接:
KEGG: bpe:BP3783
STRING: 257313.BP3783
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