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rbm24 Antibody, FITC conjugated

Rare Species
  • 中文名稱:
    rbm24兔多克隆抗體, FITC偶聯(lián)
  • 貨號(hào):
    CSB-PA745088LC01DIL
  • 規(guī)格:
    ¥880
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Danio rerio (Zebrafish) (Brachydanio rerio) rbm24 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    rbm24
  • 別名:
    rbm24 antibody; RNA-binding protein 24 antibody; RNA-binding motif protein 24 antibody; RNA-binding protein SEB-4 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Zebrafish
  • 免疫原:
    Recombinant Zebrafish RNA-binding protein 24 protein (2-78AA)
  • 免疫原種屬:
    Danio rerio (Zebrafish) (Brachydanio rerio)
  • 標(biāo)記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Multifunctional RNA-binding protein involved in the regulation of pre-mRNA splicing, mRNA stability and mRNA translation important for cell fate decision and differentiation. Plays a major role in pre-mRNA alternative splicing regulation. Mediates preferentially muscle-specific exon inclusion in numerous mRNAs important for striated cardiac and skeletal muscle cell differentiation. Binds to intronic splicing enhancer (ISE) composed of stretches of GU-rich motifs localized in flanking intron of exon that will be included by alternative splicing. Involved in embryonic stem cell (ESC) transition to cardiac cell differentiation by promoting pre-mRNA alternative splicing events of several pluripotency and/or differentiation genes. Plays a role in the regulation of mRNA stability and mRNA translation to which it is bound. Involved in myogenic differentiation by regulating myog levels. Binds to a huge amount of mRNAs. Required for embryonic heart development, sarcomer and M-band formation in striated muscles.
  • 基因功能參考文獻(xiàn):
    1. Both Rbm24a and Rbm24b are also required for normal somite and craniofacial development. PMID: 25170925
    2. Rbm24 involving in the regulation of cardiac gene expression, sarcomeric assembly, and cardiac contractility. PMID: 22345307
    3. rbm24a is a key developmental cardiac genes with unequal roles in cardiovascular formation PMID: 22011202
  • 亞細(xì)胞定位:
    Nucleus. Cytoplasm.
  • 數(shù)據(jù)庫(kù)鏈接: