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ALPG Recombinant Monoclonal Antibody

  • 中文名稱：
    ALPG重組抗體
  • 貨號：
    CSB-RA001633MA1HU
  • 規(guī)格：
    ￥1320
  • 圖片：
    • The Binding Activity of Human ALPG with Anti-ALPG Recombinant Antibody
      Activity: Measured by its binding ability in a functional ELISA. Immobilized Human ALPG (CSB-MP001633HU) at 2 μg/mL can bind Anti-ALPG recombinant antibody , the EC50 is 14.09-23.17 ng/mL.
    • The Binding Activity of Human ALPP with Anti-ALPP/ALPG Recombinant Antibody
      Activity: Measured by its binding ability in a functional ELISA. Immobilized Human ALPP (CSB-MP001632HU) at 2 μg/mL can bind Anti-ALPP/ALPG recombinant antibody. The EC50 is 4.478-5.236 ng/mL.
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品描述：
    CSB-RA001633MA1HU是針對ALPG（堿性磷酸酶胎盤型）的重組單克隆抗體，靶向ALPG蛋白的特定表位。ALPG（亦稱PLAP）屬于堿性磷酸酶家族，主要參與磷酸酯代謝，并在胎盤組織及某些腫瘤細(xì)胞中特異性高表達(dá)，其表達(dá)水平與生殖細(xì)胞腫瘤、卵巢癌等疾病的生物學(xué)行為相關(guān)。本抗體采用重組蛋白免疫技術(shù)制備，經(jīng)ELISA平臺嚴(yán)格驗證，展現(xiàn)出高特異性和靈敏性，可與天然及重組ALPG蛋白穩(wěn)定結(jié)合，且不同批次間性能高度一致。其應(yīng)用場景涵蓋體外檢測實驗，包括但不限于ELISA法檢測細(xì)胞裂解液或血清樣本中ALPG的定量分析，適用于生殖生物學(xué)、腫瘤標(biāo)志物篩選及疾病機(jī)制研究等領(lǐng)域。該產(chǎn)品經(jīng)過重組蛋白親和純化，確保低內(nèi)毒素及交叉反應(yīng)性，為科研人員提供穩(wěn)定可靠的工具，滿足蛋白質(zhì)功能研究、疾病模型構(gòu)建及生物標(biāo)志物開發(fā)等需求，所有數(shù)據(jù)均通過標(biāo)準(zhǔn)化的質(zhì)控流程驗證。
  • Uniprot No.：
  • 基因名：
  • 別名：
    ALPG Recombinant Monoclonal Antibody
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human ALPG protein
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類型：
    Monoclonal
  • 抗體亞型：
    hIgG1
  • 純化方式：
    Affinity-chromatography
  • 克隆號：
    29A5
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Alkaline phosphatase that can hydrolyze various phosphate compounds.
  • 基因功能參考文獻(xiàn)：
    1. aptamer-mediated identification of ALPPL-2 on the cell surface and cell secretions of pancreatic cancer cells supports its potential use in the serum- and membrane-based diagnosis of PDAC PMID: 23467613
    2. These results indicate that IAP is strongly involved in chylomicron formation and fatty acid metabolism might change among ABO blood type. PMID: 16412386
    3. Premature induction of hypertrophy-related molecules (type X collagen and matrix metalloproteinase 13) occurred before production of type II collagen and was followed by up-regulation of alkaline phosphatase activity. PMID: 17009260
  • 亞細(xì)胞定位：
    Cell membrane; Lipid-anchor, GPI-anchor.
  • 蛋白家族：
    Alkaline phosphatase family
  • 組織特異性：
    Trace amounts in the testis and thymus, and in elevated amounts in germ cell tumors.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 441

    OMIM: 171810

    KEGG: hsa:251

    STRING: 9606.ENSP00000295453

    UniGene: Hs.333509