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CLDN6/9 Recombinant Monoclonal Antibody

  • 中文名稱：
    CLDN6/9重組抗體
  • 貨號(hào)：
    CSB-RA005508MA3HU
  • 規(guī)格：
    ￥1320
  • 圖片：
    • The Binding Activity of Human CLDN6 with Anti-CLDN6-9 recombinant antibody
      Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CLDN6 (CSB-MP005508HU(A4)) at 10 μg/mL can bind Anti-CLDN6-9 recombinant antibody. The EC50 is 1.189-1.618 ng/mL. The VLPs (CSB-MP3838) is negative control.
    • The Binding Activity of Human CLDN6 with Anti-CLDN6-9 recombinant antibody
      Activity: Measured by its binding ability in a functional ELISA. Immobilized Human CLDN6-9 (CSB-MP005511HU) at 10 μg/mL can bind Anti-CLDN6-9 recombinant antibody. The EC50 is 2.876-3.657 ng/mL. The VLPs (CSB-MP3838) is negative control.
    • Untransfected HEK-293T cells (green line) and transfected Human CLDN6 HEK-293T stable cells (red line) were stained with anti-CLDN6/9 antibody(CSB-RA005508MA3HU) (2μg/1*106cells), washed and then followed by APC-conjugated anti-Mouse IgG Fc antibody and analyzed with flow cytometry.
    • Untransfected CHO-K1*106cells), washed and then followed by APC-conjugated anti-Mouse IgG Fc antibody and analyzed with flow cytometry.
    • Untransfected HEK-293T cells (green line) and transfected Human CLDN9 HEK-293T stable cells (red line) were stained with anti-CLDN6/9 antibody (CSB-RA005508MA3HU) (2μg/1*106cells), washed and then followed by APC-conjugated anti-Mouse IgG Fc antibody and analyzed with flow cytometry.
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品描述：
    CSB-RA005508MA3HU CLDN6/9重組單克隆抗體是針對(duì)緊密連接蛋白CLDN6和CLDN9開發(fā)的高特異性科研工具。該抗體采用重組表達(dá)技術(shù)制備，具有優(yōu)異的批次穩(wěn)定性和可重復(fù)性。靶標(biāo)CLDN6和CLDN9屬于跨膜緊密連接蛋白家族成員，參與調(diào)控細(xì)胞間連接屏障功能，其異常表達(dá)與多種上皮組織生理過程及病理狀態(tài)密切相關(guān)。經(jīng)實(shí)驗(yàn)驗(yàn)證，本產(chǎn)品在流式細(xì)胞術(shù)（FC）中展現(xiàn)出1:50-1:200的高效檢測(cè)靈敏度，同時(shí)在ELISA平臺(tái)中具備可靠的抗原結(jié)合能力，適用于體外樣本中目標(biāo)蛋白的定性與半定量分析。推薦應(yīng)用于細(xì)胞極性研究、上皮屏障功能模型構(gòu)建、腫瘤微環(huán)境分析等科研場(chǎng)景，特別適用于通過流式檢測(cè)細(xì)胞表面CLDN6/9的動(dòng)態(tài)表達(dá)，或利用ELISA技術(shù)監(jiān)測(cè)特定培養(yǎng)體系中蛋白表達(dá)水平變化，為細(xì)胞連接機(jī)制及相關(guān)信號(hào)通路研究提供精準(zhǔn)檢測(cè)方案。
  • 基因名：
    CLDN6/9
  • 別名：
    Claudin-6 antibody; Claudin6 antibody; CLD6_HUMAN antibody; CLDN 6 antibody; CLDN6 antibody; OTTHUMP00000159248 antibody; Skullin 2 antibody; Skullin antibody; UNQ757/PRO1488 antibody
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human CLDN6/9 protein
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類型：
    Monoclonal
  • 抗體亞型：
    mFc2a
  • 純化方式：
    Affinity-chromatography
  • 克隆號(hào)：
    9E2
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, FC
  • 推薦稀釋比：
    Application Recommended Dilution
    FC 1:50-1:200
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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