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Human IgG1&Igκ Isotype Recombinant Monoclonal Antibody

  • 中文名稱:
    Human IgG1&Igκ Isotype Recombinant Monoclonal Antibody
  • 貨號:
    CSB-RA011156MA1HU
  • 規(guī)格:
    ¥1320
  • 圖片:
    • Untransfected MC38 cells and transfected Human TSPAN8 MC38 stable cells were stained with Human IgG1&Igκ Isotype Control (CSB-RA011156MA1HU) and anti-TSPAN8 antibody (CSB-RA025166MA1HU) (2μg/1*106cells), washed and then followed by FITC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry.
    • HT29 cells were stained with Human IgG1&Igκ Isotype Control (CSB-RA011156MA1HU)(green line) and anti-TSPAN8 antibody (CSB-RA882142MA1HU) (2μg/1*106cells) (red line), washed and then followed by FITC-conjugated anti-Human IgG Fc antibody and analyzed with flow cytometry.
    • The purity of Human IgG1&Igκ Isotype was greater than 95% as determined by SEC-HPLC
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
    IgG1
  • 別名:
    Human IgG1
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human IgG1 protein
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Monoclonal
  • 抗體亞型:
    hIgG1
  • 純化方式:
    Affinity-chromatography
  • 克隆號:
    4D2
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    FC
  • 推薦稀釋比:
    Application Recommended Dilution
    FC 1:50-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    Constant region of immunoglobulin heavy chains. Immunoglobulins, also known as antibodies, are membrane-bound or secreted glycoproteins produced by B lymphocytes. In the recognition phase of humoral immunity, the membrane-bound immunoglobulins serve as receptors which, upon binding of a specific antigen, trigger the clonal expansion and differentiation of B lymphocytes into immunoglobulins-secreting plasma cells. Secreted immunoglobulins mediate the effector phase of humoral immunity, which results in the elimination of bound antigens. The antigen binding site is formed by the variable domain of one heavy chain, together with that of its associated light chain. Thus, each immunoglobulin has two antigen binding sites with remarkable affinity for a particular antigen. The variable domains are assembled by a process called V-(D)-J rearrangement and can then be subjected to somatic hypermutations which, after exposure to antigen and selection, allow affinity maturation for a particular antigen.
  • 相關(guān)疾病:
    Multiple myeloma (MM)
  • 亞細胞定位:
    Secreted. Cell membrane.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 5525

    OMIM: 147100

    UniGene: Hs.510635