SN38 Recombinant Monoclonal Antibody
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中文名稱:SN38重組抗體
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貨號(hào):CSB-RA187707I1m
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規(guī)格:¥3000
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圖片:
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The Binding Activity of Labetuzumab govitecan (Synonyms: IMMU 130; hMN-14-SN-38) with Anti-SN38 antibody
Activity: Measured by its binding ability in a functional ELISA. Immobilized Labetuzumab govitecan (Synonyms: IMMU 130; hMN-14-SN-38) at 2 μg/mL can bind Anti-SN38 antibody, the EC50 is 3.326 to 4.721 ng/mL.
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其他:
產(chǎn)品詳情
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產(chǎn)品描述:SN38 Recombinant Monoclonal Antibody(Code: CSB-RA187707I1m)是一種高特異性抗體,靶向SN38分子(7-ethyl-10-hydroxycamptothecin),該分子是拓?fù)洚悩?gòu)酶I抑制劑伊立替康的活性代謝產(chǎn)物,在腫瘤研究領(lǐng)域被廣泛用于誘導(dǎo)DNA損傷及細(xì)胞凋亡機(jī)制研究。本抗體通過(guò)重組技術(shù)制備,經(jīng)ELISA方法嚴(yán)格驗(yàn)證,在1:5000至1:50000的寬泛稀釋范圍內(nèi)表現(xiàn)出優(yōu)異的檢測(cè)靈敏度和線性關(guān)系,可精準(zhǔn)識(shí)別天然構(gòu)象的SN38分子。其高批次穩(wěn)定性與低交叉反應(yīng)性設(shè)計(jì),適用于定量分析SN38在細(xì)胞模型或體外藥理學(xué)研究中的分布與作用,例如評(píng)估藥物遞送效率、代謝動(dòng)力學(xué)或腫瘤細(xì)胞耐藥性機(jī)制等實(shí)驗(yàn)場(chǎng)景。推薦應(yīng)用于ELISA平臺(tái)檢測(cè),支持細(xì)胞培養(yǎng)上清、裂解液等樣本類(lèi)型的分析,為抗腫瘤藥物開(kāi)發(fā)及分子毒理學(xué)研究提供可靠工具。該產(chǎn)品僅供科研使用,不涉及任何臨床相關(guān)用途。
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基因名:SN38
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別名:SN38, 7-Ethyl-10-hydroxycamptothecin
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反應(yīng)種屬:Human
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免疫原:SN38-BSA
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標(biāo)記方式:Non-conjugated
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克隆類(lèi)型:Monoclonal
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抗體亞型:IgG2a
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純化方式:Affinity-chromatography
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克隆號(hào):10G11D5
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濃度:It differs from different batches. Please contact us to confirm it.
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保存緩沖液:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 -
產(chǎn)品提供形式:Liquid
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應(yīng)用范圍:ELISA
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推薦稀釋比:
Application Recommended Dilution ELISA 1:5000-1:50000 -
Protocols:
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儲(chǔ)存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途:For Research Use Only. Not for use in diagnostic or therapeutic procedures.
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