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GRIA2/GRIA3 Recombinant Monoclonal Antibody

  • 中文名稱：
    GRIA2/GRIA3重組抗體
  • 貨號(hào)：
    CSB-RA009900A0HU
  • 規(guī)格：
    ￥1320
  • 圖片：
    • Immunofluorescence staining of MCF-7 cells with CSB-RA009900A0HU at 1:56, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4℃. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG (H+L).
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品描述：
    CSB-RA009900A0HU重組單克隆抗體是針對(duì)谷氨酸受體亞基GRIA2和GRIA3開(kāi)發(fā)的高特異性科研工具。該抗體靶向的GRIA2（GluA2）和GRIA3（GluA3）是離子型AMPA受體的核心組成單元，通過(guò)介導(dǎo)中樞神經(jīng)系統(tǒng)快速興奮性突觸傳遞參與學(xué)習(xí)記憶及神經(jīng)可塑性調(diào)控，其功能異常與阿爾茨海默病、癲癇等神經(jīng)系統(tǒng)疾病密切相關(guān)。經(jīng)嚴(yán)格驗(yàn)證，本產(chǎn)品在ELISA實(shí)驗(yàn)中展現(xiàn)出優(yōu)異的抗原結(jié)合能力，同時(shí)適用于免疫熒光實(shí)驗(yàn)（推薦稀釋比1:20-1:200），能夠清晰定位細(xì)胞或組織中目標(biāo)蛋白的表達(dá)分布。作為重組單克隆抗體，其具備高批次間一致性和低交叉反應(yīng)性特點(diǎn)，適用于神經(jīng)突觸蛋白互作研究、受體亞基表達(dá)模式分析以及疾病模型中AMPA受體功能探究等基礎(chǔ)科研領(lǐng)域，為探索神經(jīng)信號(hào)傳導(dǎo)機(jī)制及相關(guān)病理過(guò)程提供可靠實(shí)驗(yàn)支持。
  • Uniprot No.：
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    A synthesized peptide derived from human GRIA2/GRIA3
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類型：
    Monoclonal
  • 抗體亞型：
    Rabbit IgG
  • 純化方式：
    Affinity-chromatography
  • 克隆號(hào)：
    4C3
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IF 1:20-1:200
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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