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  4. Hydroxyl-Histone H2A type 1-B/E (Y39) Recombinant Monoclonal Antibody

Hydroxyl-Histone H2A type 1-B/E (Y39) Recombinant Monoclonal Antibody

  • 中文名稱：
    羥基-組蛋白 H2A type 1-B/E (Y39)重組抗體
  • 貨號(hào)：
    CSB-RA010385A39ohHU
  • 規(guī)格：
    ￥1320
  • 圖片：
    • Western Blot
      Positive WB detected in Mouse spleen tissue All lanes Hydroxyl-Histone H2A type 1-B/E (Y39) antibody at 1.05μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 14 KDa
      Observed band size: 14 KDa
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品描述：
    CSB-RA010385A39ohHU是一種特異性識(shí)別組蛋白H2A 1-B/E亞型Y39位點(diǎn)羥基化修飾的高純度抗體。組蛋白H2A是染色質(zhì)核心成分之一，其翻譯后修飾（如羥基化）在表觀遺傳調(diào)控、DNA損傷修復(fù)及基因表達(dá)中發(fā)揮重要作用。該抗體經(jīng)ELISA和蛋白質(zhì)免疫印跡（WB）嚴(yán)格驗(yàn)證，在WB應(yīng)用中展現(xiàn)出優(yōu)異性能，推薦稀釋比例為1:500-1:2000，可精準(zhǔn)識(shí)別目標(biāo)蛋白，檢測(cè)結(jié)果呈現(xiàn)清晰的條帶信號(hào)且背景干擾低，適用于細(xì)胞或組織樣本分析。該產(chǎn)品適用于探索組蛋白修飾的動(dòng)態(tài)調(diào)控機(jī)制、染色質(zhì)重塑過程以及表觀遺傳相關(guān)疾病的基礎(chǔ)研究，為解析DNA修復(fù)通路或細(xì)胞周期調(diào)控提供可靠工具。重組單克隆抗體技術(shù)確保產(chǎn)品批次間高度一致性，滿足長(zhǎng)期實(shí)驗(yàn)的穩(wěn)定性需求，是分子生物學(xué)和表觀遺傳學(xué)研究的理想選擇。
  • Uniprot No.：
  • 基因名：
    HIST1H2AB
  • 別名：
    H2a 615 antibody; H2A antibody; H2A GL101 antibody; H2A histone family member A antibody; H2A.1 antibody; H2A.2 antibody; H2A/a antibody; H2A/m antibody; H2A/O antibody; H2A/q antibody; H2A1B_HUMAN antibody; H2AFA antibody; H2AFE antibody; H2AFL antibody; H2AFM antibody; H2AFO antibody; H2AFQ antibody; HIST1H2AE antibody; HIST1H2AJ antibody; HIST2H2AA antibody; HIST2H2AA3 antibody; HIST2H2AB antibody; HIST2H2AC antibody; Histone 1 H2ae antibody; Histone 2 H2aa3 antibody; Histone 2 H2ab antibody; Histone 2 H2ac antibody; Histone H2A type 1 B antibody; Histone H2A type 1 C antibody; Histone H2A type 1 E antibody; Histone H2A type 1 J antibody; Histone H2A type 1-B/E antibody; Histone H2A.2 antibody; Histone H2A/a antibody; Histone H2A/m antibody; MGC74460 antibody
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    A synthesized peptide
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 克隆類型：
    Monoclonal
  • 抗體亞型：
    Rabbit IgG
  • 純化方式：
    Affinity-chromatography
  • 克隆號(hào)：
    3B12
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
  • 亞細(xì)胞定位：
    Nucleus. Chromosome.
  • 蛋白家族：
    Histone H2A family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 4734

    OMIM: 602786

    KEGG: hsa:3012

    STRING: 9606.ENSP00000303373

    UniGene: Hs.121017