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N Recombinant Monoclonal Antibody

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  • 中文名稱：
    N重組抗體
  • 貨號：
    CSB-RA33255A0GMY
  • 規(guī)格：
    ￥2310
  • 圖片：
    • The Binding Activity of SARS-CoV-2-N Antibody with SARS-CoV-2-N
      Activity: Measured by its binding ability in a functional ELISA. Immobilized SARS-CoV-2-N (CSB-EP3325GMY) at 2 μg/ml can bind SARS-CoV-2-N Antibody, the EC50 is 6.892 ng/ml.
    • In the Colloidal Gold Immunochromatography Assay detection system, the background of antibody (CSB-RA33255A0GMY) is clean, the detection limit can be as low as 446.4ng/ml (31.25ng/0.07ml), and the sensitivity is very good.
    • ELISA: Immobilize various types of SARS proteins at concentration of 2μg/ml on solid substrate, then react with SARS-CoV-2-N Antibody at concentration of 100μg/ml, 10μg/ml and 1μg/ml. It shows the SARS-CoV-2-N Antibody (CSB-RA33255A0GMY) is specific for SARS-CoV-2-N protein, without any cross-reactivity with NL63-CoV, HCoV-OC43, HCoV-229E or HCoV-HKU1.
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品描述：
    CSB-RA33255A0GMY N Recombinant Monoclonal Antibody是針對病毒核衣殼蛋白（N蛋白）開發(fā)的高特異性抗體。N蛋白作為病毒核心結(jié)構(gòu)蛋白，在病毒基因組包裝、RNA結(jié)合及宿主免疫調(diào)控中發(fā)揮關(guān)鍵作用，是病原體檢測的重要靶標。本抗體采用重組表達技術(shù)制備，具有優(yōu)異的批次一致性和穩(wěn)定性，經(jīng)ELISA和膠體金免疫層析（GICA）驗證，可精準識別天然構(gòu)象的N蛋白抗原，其靈敏度在ELISA應(yīng)用中達到1:10000-1:50000稀釋度，在GICA檢測中適用于1:500-1:2000稀釋范圍，滿足高分辨率和快速檢測需求。該產(chǎn)品適用于病毒抗原的體外定性或半定量分析，可支持病毒學(xué)基礎(chǔ)研究、免疫學(xué)檢測試劑開發(fā)及抗病毒藥物篩選等科研場景。通過嚴格的交叉反應(yīng)性驗證和親和力測試，確保其對目標蛋白的特異性識別，且符合ISO質(zhì)量管理體系標準，適用于要求高重復(fù)性的實驗體系。本品僅限科研用途，不涉及其他領(lǐng)域應(yīng)用。
  • Uniprot No.：
  • 別名：
    N; Nucleoprotein; N; Nucleocapsid protein; NC; Protein N
  • 反應(yīng)種屬：
    Human Novel Coronavirus (SARS-CoV-2/ 2019-nCoV)
  • 免疫原：
    Recombinant Human Novel Coronavirus Nucleoprotein (N) (1-419aa)(CSB-EP3325GMY)
  • 免疫原種屬：
    Human Novel Coronavirus (SARS-CoV-2/ 2019-nCoV)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Monoclonal
  • 抗體亞型：
    Monoclonal mouse (varialbe region)/human (kappa/IgG1 constant)chimeric antibody
  • 純化方式：
    Affinity-chromatography
  • 克隆號：
    1A6
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, GICA
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:10000-1:50000
    GICA 1:500-1:2000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication. May modulate transforming growth factor-beta signaling by binding host smad3.
  • 亞細胞定位：
    Virion. Host cytoplasm.
  • 蛋白家族：
    Betacoronavirus nucleocapsid protein family