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  4. Recombinant Borrelia burgdorferi Carbon storage regulator homolog (csrA)

Recombinant Borrelia burgdorferi Carbon storage regulator homolog (csrA)

  • 中文名稱：
    Recombinant Borrelia burgdorferi Carbon storage regulator homolog(csrA)
  • 貨號：
    CSB-YP524387BUD
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Borrelia burgdorferi Carbon storage regulator homolog(csrA)
  • 貨號：
    CSB-EP524387BUD
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Borrelia burgdorferi Carbon storage regulator homolog(csrA)
  • 貨號：
    CSB-EP524387BUD-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Borrelia burgdorferi Carbon storage regulator homolog(csrA)
  • 貨號：
    CSB-BP524387BUD
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Borrelia burgdorferi Carbon storage regulator homolog(csrA)
  • 貨號：
    CSB-MP524387BUD
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    csrA
  • Uniprot No.：
  • 別名：
    csrA; BB_0184Translational regulator CsrA
  • 種屬：
    Borrelia burgdorferi (strain ATCC 35210 / B31 / CIP 102532 / DSM 4680)
  • 蛋白長度：
    full length protein
  • 表達區(qū)域：
    1-81
  • 氨基酸序列
    MLVLSRKANE SIKINSDIEV LILEIKKDAV KIAIKAPENI KIFRSEIYEF IIEENKKSLL KDKHNISKIK SLFNHYFKNE N
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.
  • 基因功能參考文獻：
    1. These observations reveal conserved and unique functions of CsrABb that regulate adaptive gene expression in B. burgdorferi PMID: 23753623
    2. The authors found that CsrA(Bb) bound to the flaB transcripts via two binding sites, and this binding inhibited the synthesis of FlaB at the translational level. PMID: 21999436
    3. CsrA(Bb) may influence the infectivity of B. burgdorferi via regulation of acetate metabolism and subsequent activation of the Rrp2-RpoN-RpoS pathway. PMID: 21173314
    4. CsrABb plays a role in the regulation of expression of pathophysiological determinants of B. burgdorferi PMID: 19737901
  • 亞細胞定位：
    Cytoplasm.
  • 蛋白家族：
    CsrA/RsmA family
  • 數(shù)據庫鏈接：

    KEGG: bbu:BB_0184

    STRING: 224326.BB_0184