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  4. Recombinant Drosophila melanogaster Cytoplasmic FMR1-interacting protein (Sra-1), partial

Recombinant Drosophila melanogaster Cytoplasmic FMR1-interacting protein (Sra-1), partial

  • 中文名稱：
    黑腹果蠅Sra-1重組蛋白
  • 貨號：
    CSB-YP893270DLU
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    黑腹果蠅Sra-1重組蛋白
  • 貨號：
    CSB-EP893270DLU
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    黑腹果蠅Sra-1重組蛋白
  • 貨號：
    CSB-EP893270DLU-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    黑腹果蠅Sra-1重組蛋白
  • 貨號：
    CSB-BP893270DLU
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    黑腹果蠅Sra-1重組蛋白
  • 貨號：
    CSB-MP893270DLU
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Sra-1
  • Uniprot No.：
  • 別名：
    Sra-1; Cyfip; CG4931Cytoplasmic FMR1-interacting protein; Specifically Rac1-associated protein 1; DSra-1
  • 種屬：
    Drosophila melanogaster (Fruit fly)
  • 蛋白長度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能：
    Plays a role in guidance and morphology of central and peripheral axons and in synaptic morphology. Also required for formation of cell membrane protrusions and for bristle development. Plays a role in regulating mitochondrial activity, energy metabolism and membrane potential which maintains normal gamma-aminobutyric acid (GABA) signaling and ensures normal social behavior.
  • 基因功能參考文獻(xiàn)：
    1. These results illustrate a new model to explain the cellular roles of FMRP and CYFIP1 and the molecular significance of their interaction. PMID: 28183735
    2. We propose that Cyfip regulates synapse development and endocytosis by inhibiting actin assembly. PMID: 23593037
    3. Mutations in WAVE/SCAR and in ARP2/3 complex subunits but not in WASP, another major regulator of Actin nucleation, phenocopy CYFIP defects. Thus, the CYFIP-SCAR-ARP2/3 pathway orchestrates specific tissue remodeling processes PMID: 21884694
    4. CYFIP specifically expressed in the nervous system; mutations affect axons and synapses, much like mutations in dFMR1 and Rho GTPase dRac1; CYFIP acts as a dRac1 effector that antagonizes FMR1 function PMID: 12818175
  • 亞細(xì)胞定位：
    Cytoplasm.
  • 蛋白家族：
    CYFIP family
  • 組織特異性：
    In the embryo, expressed mainly in the gut and in the developing central nervous system where high levels of expression are found in the CNS neuropile. Expression in the gut diminishes as development proceeds (at protein level). In the adult, expressed sp
  • 數(shù)據(jù)庫鏈接：

    KEGG: dme:Dmel_CG4931

    STRING: 7227.FBpp0082541

    UniGene: Dm.3506