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  4. Recombinant Drosophila melanogaster Death domain-containing adapter protein BG4 (BG4)

Recombinant Drosophila melanogaster Death domain-containing adapter protein BG4 (BG4)

  • 中文名稱：
    黑腹果蠅Fadd重組蛋白
  • 貨號：
    CSB-YP893221DLU
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    黑腹果蠅Fadd重組蛋白
  • 貨號：
    CSB-EP893221DLU
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    黑腹果蠅Fadd重組蛋白
  • 貨號：
    CSB-EP893221DLU-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    黑腹果蠅Fadd重組蛋白
  • 貨號：
    CSB-BP893221DLU
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    黑腹果蠅Fadd重組蛋白
  • 貨號：
    CSB-MP893221DLU
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Fadd; BG4; CG12297Fas-associated death domain protein; Death domain-containing adapter protein BG4; FAS-associating death domain-containing protein; dFADD
  • 種屬：
    Drosophila melanogaster (Fruit fly)
  • 蛋白長度：
    full length protein
  • 表達(dá)區(qū)域：
    1-239
  • 氨基酸序列
    MTAGRHWSYD SLKQIAIDGC TENVEQLKLI FVEEIGSRRR SDCIRTIEDL IDCLERADEL SEYNVEPLRR ISGNMPQLIE ALSAYTKPEN ILGHPVNLYQ ELRLAEELRQ QLRIAPASQN AQPSVSELAA AVPPTAIQNY ATPAAFTDHK RTMVFKKISE ELGRYWRRLG RSAGIGEGQM DTIEERYPHD LKSQILRLLQ LIEEDDCHDP KHFLLRLCRA LGDCGRNDLR KRVEQIMSH
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Component of the IMD signaling pathway and is required for the host defense against Gram-negative bacteria. Interacts with Dredd, promotes cleavage of Dredd and is necessary and sufficient for enhancing Dredd-induced apoptosis.
  • 基因功能參考文獻(xiàn)：
    1. demonstrate that dFADD is a novel component of the immune deficiency pathway; double-stranded RNA expression reduces the induction of antibacterial peptide-encoding genes after infection and renders the fly susceptible to Gram-negative bacterial infection PMID: 12123572
    2. dFADD acts downstream of IMD protein in the pathway that controls inducibility of the antibacterial peptide genes PMID: 12433364
  • 亞細(xì)胞定位：
    Cytoplasm.
  • 數(shù)據(jù)庫鏈接：

    KEGG: dme:Dmel_CG12297

    STRING: 7227.FBpp0083574

    UniGene: Dm.1273