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  4. Recombinant Drosophila melanogaster Probable Ras GTPase-activating protein (CG42684), partial

Recombinant Drosophila melanogaster Probable Ras GTPase-activating protein (CG42684), partial

  • 中文名稱：
    Recombinant Drosophila melanogaster Probable Ras GTPase-activating protein(CG42684) ,partial
  • 貨號：
    CSB-YP844692DLU
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Drosophila melanogaster Probable Ras GTPase-activating protein(CG42684) ,partial
  • 貨號：
    CSB-EP844692DLU
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Drosophila melanogaster Probable Ras GTPase-activating protein(CG42684) ,partial
  • 貨號：
    CSB-EP844692DLU-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Drosophila melanogaster Probable Ras GTPase-activating protein(CG42684) ,partial
  • 貨號：
    CSB-BP844692DLU
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Drosophila melanogaster Probable Ras GTPase-activating protein(CG42684) ,partial
  • 貨號：
    CSB-MP844692DLU
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    CG42684
  • Uniprot No.：
  • 別名：
    raskol; CG42684Ras GTPase-activating protein raskol
  • 種屬：
    Drosophila melanogaster (Fruit fly)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    GTPase-activating protein, which acts as a negative regulator for some members of the Ras family. Probably decreases their signaling activity by stimulating their intrinsic GTPase activity, thereby lowering the levels of the GTP-bound active form. Functions with DE-cadherin (shg) to promote embryonic border cell (BC) migration and adhesion by regulating the distribution of actin protrusions in BCs. Promotes shg-mediated adhesion at the BC interfaces and likely maintains BC cluster adhesion during BC detachment from the follicular epithelium and subsequent BC migration. Also required for restricting the development of actin-rich protrusions to the front of migrating BC clusters thus ensuring unidirectional BC migration. Possibly functions by suppressing Rac1 signaling in non-leading BCs, thus limiting its activity to leading BCs where it initiates localized actin cytoskeleton remodeling to produce the polarized protrusions.
  • 亞細胞定位：
    Cytoplasm. Cell membrane; Peripheral membrane protein. Apical cell membrane; Peripheral membrane protein.
  • 數(shù)據(jù)庫鏈接：

    KEGG: dme:Dmel_CG42684

    STRING: 7227.FBpp0291973

    UniGene: Dm.197