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  4. Recombinant Mouse Cartilage-associated protein (Crtap)

Recombinant Mouse Cartilage-associated protein (Crtap)

  • 中文名稱：
    Recombinant Mouse Cartilage-associated protein(Crtap)
  • 貨號(hào)：
    CSB-YP880448MO
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Mouse Cartilage-associated protein(Crtap)
  • 貨號(hào)：
    CSB-EP880448MO
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Mouse Cartilage-associated protein(Crtap)
  • 貨號(hào)：
    CSB-EP880448MO-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Mouse Cartilage-associated protein(Crtap)
  • 貨號(hào)：
    CSB-BP880448MO
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Mouse Cartilage-associated protein(Crtap)
  • 貨號(hào)：
    CSB-MP880448MO
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Crtap
  • Uniprot No.：
  • 別名：
    Crtap; Casp; Cartilage-associated protein
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達(dá)區(qū)域：
    26-400
  • 氨基酸序列
    QYERY SFRSFPRDEL MPLESAYRHA LDQYSGEHWA ESVGYLEVSL RLHRLLRDSE AFCHRNCSAA TPAPAPAGPA SHAELRLFGS VLRRAQCLKR CKQGLPAFRQ SQPSRSVLAD FQQREPYKFL QFAYFKANDL PKAIAAAHTY LLKHPDDEMM KRNMEYYKSL PGAEDHIKDL ETKSYESLFV RAVRAYNGEN WRTSISDMEL ALPDFLKAFY ECLAACEGSR EIKDFKDFYL SIADHYVEVL ECKIRCEETL TPVIGGYPVE KFVATMYHYL QFAYYKLNDL KNAAPCAVSY LLFDQSDRVM QQNLVYYQYH RDKWGLSDEH FQPRPEAVQF FNVTTLQKEL YDFAQEHLMD DDEGEVVEYV DDLLETEESA
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Necessary for efficient 3-hydroxylation of fibrillar collagen prolyl residues.
  • 基因功能參考文獻(xiàn)：
    1. This substitution abolished P3h1 activity but retained ability to form a complex with Crtap and thus the collagen chaperone function. PMID: 24465224
    2. In Crtap-deficient mice, the mineral content of the bone matrix is abnormally high; there are increased mineral densities at all measured sites for murine femora compared to control animals. PMID: 19895918
    3. CRTAP mutations are associated with the clinical spectrum of recessive osteogenesis imperfecta, including the type II and VII forms PMID: 17055431
  • 相關(guān)疾?。?/div>
    Defects in Crtap are a cause of osteochondrodysplasia characterized by severe osteoporosis and decreased osteoid production.
  • 亞細(xì)胞定位：
    Secreted, extracellular space, extracellular matrix.
  • 蛋白家族：
    Leprecan family
  • 組織特異性：
    Found in articular chondrocytes. Expressed in a variety of tissues.
  • 數(shù)據(jù)庫鏈接：