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  4. Recombinant Mouse Developmentally-regulated GTP-binding protein 2 (Drg2)

Recombinant Mouse Developmentally-regulated GTP-binding protein 2 (Drg2)

  • 中文名稱：
    小鼠Drg2重組蛋白
  • 貨號(hào)：
    CSB-YP874104MO
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Drg2重組蛋白
  • 貨號(hào)：
    CSB-EP874104MO
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Drg2重組蛋白
  • 貨號(hào)：
    CSB-EP874104MO-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Drg2重組蛋白
  • 貨號(hào)：
    CSB-BP874104MO
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Drg2重組蛋白
  • 貨號(hào)：
    CSB-MP874104MO
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Drg2
  • Uniprot No.：
  • 別名：
    Drg2Developmentally-regulated GTP-binding protein 2; DRG-2; Translation factor GTPase DRG2; TRAFAC GTPase DRG2; EC 3.6.5.-
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達(dá)區(qū)域：
    1-364
  • 氨基酸序列
    MGILEKISEI EKEIARTQKN KATEYHLGLL KAKLAKYRAQ LLEPSKSASS KGEGFDVMKS GDARVALIGF PSVGKSTFLS LMTSTASEAA SYEFTTLTCI PGVIEYKGAN IQLLDLPGII EGAAQGRGRG RQVIAVARTA DVVVMMLDAT KGDVQRSLLE KELESVGIRL NKHKPNIYFK PKKGGGISFN STVTLTQCSE KLVQLILHEY KIFNAEVLFR EDCSPDDFID VIVGNRVYMP CLYVYNKIDQ ISMEEVDRLA RKPNSVVISC GMKLNLDYLL EMLWEYLALT CIYTKKRGQR PDFTDAIILR KGASVEHVCH RIHRSLASQF KYALVWGTST KYSPQRVGLT HTMEHEDVIQ IVKK
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Catalyzes the conversion of GTP to GDP through hydrolysis of the gamma-phosphate bond in GTP. When hydroxylated at C-3 of 'Lys-21' by JMJD7, may bind to RNA and play a role in translation.
  • 基因功能參考文獻(xiàn)：
    1. Our results reveal a novel mechanism for regulation of membrane tubule stability mediated by DRG2. PMID: 28865956
    2. Developmentally regulated GTP-binding protein 2 ameliorates EAE by suppressing the development of TH17 cells. PMID: 24463315
    3. DRG2 is associated with survival and cytoskeleton organization of osteoclasts under influence of macrophage colony-stimulating factor, and its overexpression leads to elevated bone resorptive activity of osteoclasts, resulting in bone loss. PMID: 23360825
  • 亞細(xì)胞定位：
    Nucleus. Cytoplasm.
  • 蛋白家族：
    TRAFAC class OBG-HflX-like GTPase superfamily, OBG GTPase family
  • 組織特異性：
    Fairly high levels in liver, heart, kidney, and brain. Very low levels in lung, spleen, testis and skeletal muscle.
  • 數(shù)據(jù)庫鏈接：