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  4. Recombinant Mouse E3 ubiquitin-protein ligase RNF6 (Rnf6)

Recombinant Mouse E3 ubiquitin-protein ligase RNF6 (Rnf6)

  • 中文名稱：
    小鼠Rnf6重組蛋白
  • 貨號(hào)：
    CSB-YP872050MO
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Rnf6重組蛋白
  • 貨號(hào)：
    CSB-EP872050MO
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Rnf6重組蛋白
  • 貨號(hào)：
    CSB-EP872050MO-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Rnf6重組蛋白
  • 貨號(hào)：
    CSB-BP872050MO
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Rnf6重組蛋白
  • 貨號(hào)：
    CSB-MP872050MO
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Rnf6
  • Uniprot No.：
  • 別名：
    Rnf6; E3 ubiquitin-protein ligase RNF6; EC 2.3.2.27; RING-type E3 ubiquitin transferase RNF6; RLIM-like protein
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長(zhǎng)度：
    full length protein
  • 表達(dá)區(qū)域：
    1-667
  • 氨基酸序列
    MDPSRSRSGG SGEESSFQEN ERRWQQERLH REEAYYQFIN ELSDEDYRLM RDHNLLGTPG EITSEELQQR LERAKEQLAS QPGSDSAASD GDSESLRAHS DEDSLLRWLN TFRRTGNVTR SGQNGNQSWR AVSRTNPNSG EFGFSLEIHI NPDNRGSEMH GEDSTDIPLS GVNREHRQQR PSSPVARRTR SQTSMSSSGP RGRRGARRQG SVQGSFATLG RLRNGIGVAL GVPRVSAPRT NVINSHTNQS DGSTLRQGGR QRFGAAHIWE NGARSNVTVR NTNQRLEPIR LRPAFSSRSR SPIQRQNGTV HHNSQRQGRP VQQTGRNRSV RHRGVTRVFL EQGREHRGTD YTPLSNSRLV SRITVEEGES SRSSAATQRH PAITLDLQVR RIRPGETRDR DSIANRTRSR AGLAESTVES TSGGFHRTIS HLERSGVRTY VSTITVPLRR ISENDVVEPS SVALRSILRQ IMTGFGELSS LMEVEPASEN QSNGQRLPEV YLELSNGDAA DDSGQHGRAS SQASQAQDGA EMLAVREPAP PQARPSGSRS RRQLGRADSV VEAGTLPILR LAHFFLLNEG DDDPIRGLTK EQIDNLSTRS YEQDGVDSEL GKVCSVCISD YVAGNKLRQL PCLHEFHIHC IDRWLSENCT CPVCRRPVLE FGATSSG
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    E3 ubiquitin-protein ligase mediating 'Lys-48'-linked polyubiquitination of LIMK1 and its subsequent targeting to the proteasome for degradation. Negatively regulates axonal outgrowth through regulation of the LIMK1 turnover. Mediates 'Lys-6' and 'Lys-27'-linked polyubiquitination of AR/androgen receptor thereby modulating its transcriptional activity. May also bind DNA and function as a transcriptional regulator.
  • 基因功能參考文獻(xiàn)：
    1. Rnf6 controls cellular LIMK1 concentrations and indicate a new function for the ubiquitin/proteasome system in regulating local growth cone actin dynamics PMID: 16204183
  • 亞細(xì)胞定位：
    Nucleus. Cytoplasm. Cell projection, axon. Nucleus, PML body. Note=Localizes to the PML nuclear bodies in Sertoli cells.
  • 蛋白家族：
    RNF12 family
  • 組織特異性：
    Widely expressed with higher expression in the testis in both germ cells and Sertoli cells.
  • 數(shù)據(jù)庫鏈接：