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  4. Recombinant Mouse Microtubule-associated protein 1A (Map1a), partial

Recombinant Mouse Microtubule-associated protein 1A (Map1a), partial

  • 中文名稱：
    小鼠Map1a重組蛋白
  • 貨號：
    CSB-YP013400MO
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Map1a重組蛋白
  • 貨號：
    CSB-EP013400MO
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Map1a重組蛋白
  • 貨號：
    CSB-EP013400MO-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Map1a重組蛋白
  • 貨號：
    CSB-BP013400MO
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Map1a重組蛋白
  • 貨號：
    CSB-MP013400MO
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Map1a
  • Uniprot No.：
  • 別名：
    Map1a; Mtap1; Mtap1aMicrotubule-associated protein 1A; MAP-1A) [Cleaved into: MAP1A heavy chain; MAP1 light chain LC2]
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    Structural protein involved in the filamentous cross-bridging between microtubules and other skeletal elements.
  • 基因功能參考文獻(xiàn)：
    1. Structure of the PSD-95/MAP1A complex reveals a unique target recognition mode of the MAGUK GK domain. PMID: 28701415
    2. Mutant mice lacking MAP1A exhibited reduced synaptic plasticity. PMID: 26609151
    3. Although MAP1A and MAP1B protein levels are not affected in the tulp1-/- retina, they are no longer localized to the outer segment of photoreceptors. PMID: 24664738
    4. The interaction between the conserved COOH-terminal 125-amino acid domain (which is located in the light chains of MAP1A, MAP1B, and MAP1S) and alpha1-syntrophin is direct and occurs through the pleckstrin homology domain 2 (PH2). PMID: 23152929
    5. It was demonstrated that the gene Mtap1a modifies retinal degeneration in Tub(tub/tub) and Tulp1(tm1Pjn/tm1Pjn) mice. PMID: 22323461
    6. Data indicate that protective alleles of Mtap1a are not sufficient to rescue DW/J-Pou1f1dw/dw mutant hearing. PMID: 21840860
    7. Microtubule-associated protein 1A is a modifier of tubby hearing (moth1). PMID: 11925566
    8. Data show that two regulatory factor for X box (RFX1 and 3) binding sites in exon1 of both the mouse and human microtubule-associated protein (MAP1A) gene are important for effective transcriptional repression in non-neuronal cells. PMID: 12411430
    9. Microtubule-associated protein light chain 2 interacts with the intracellular C-terminal tail of stargazin. PMID: 15136571

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  • 亞細(xì)胞定位：
    Cytoplasm, cytoskeleton.
  • 蛋白家族：
    MAP1 family
  • 組織特異性：
    Both isoforms highly expressed in brain, and to a lesser extent in embryo. Isoform 1 is also expressed at a low level in other tissues including heart and muscle.
  • 數(shù)據(jù)庫鏈接：