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  4. Recombinant Mouse Peptidyl-tRNA hydrolase ICT1, mitochondrial (Ict1)

Recombinant Mouse Peptidyl-tRNA hydrolase ICT1, mitochondrial (Ict1)

  • 中文名稱：
    小鼠Mrpl58重組蛋白
  • 貨號：
    CSB-YP840255MO
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Mrpl58重組蛋白
  • 貨號：
    CSB-EP840255MO
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Mrpl58重組蛋白
  • 貨號：
    CSB-EP840255MO-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Mrpl58重組蛋白
  • 貨號：
    CSB-BP840255MO
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Mrpl58重組蛋白
  • 貨號：
    CSB-MP840255MO
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Mrpl58
  • Uniprot No.：
  • 別名：
    Mrpl58; Ict1; Peptidyl-tRNA hydrolase ICT1; mitochondrial; EC 3.1.1.29; 39S ribosomal protein L58; mitochondrial; MRP-L58; Immature colon carcinoma transcript 1 protein homolog
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區(qū)域：
    30-206
  • 氨基酸序列
    L HRQVDGTTFQ SIYSLDKLYP ESKGADTAWK VPEHAKQASS YIPLDRLSIS YCRSSGPGGQ NVNKVNSKAE VRFHLASADW IEEPVRQKIA LTHKNKINKA GELVLTSESS RYQFRNLAEC LQKIRDMIAE ASQVPKEPSK EDARLQRLRI EKMNRERLRQ KRLNSALKTS RRMTMD
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes.
  • 基因功能參考文獻：
    1. Because ICT1 is essential in human cells, these results suggest that ribosome rescue activity in mitochondria is required in humans PMID: 27029019
    2. solution structure of the catalytic domain of the ICT1 protein that lacks an N-terminal mitochondrial targeting signal and an unstructured C-terminal basic-residue-rich extension PMID: 20869366
  • 亞細胞定位：
    Mitochondrion.
  • 蛋白家族：
    Prokaryotic/mitochondrial release factor family, Mitochondrion-specific ribosomal protein mL62 subfamily
  • 數(shù)據(jù)庫鏈接：

    KEGG: mmu:68572

    UniGene: Mm.271062