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  4. Recombinant Mouse Serine/threonine-protein kinase ULK4 (Ulk4), partial

Recombinant Mouse Serine/threonine-protein kinase ULK4 (Ulk4), partial

  • 中文名稱：
    小鼠Ulk4重組蛋白
  • 貨號(hào)：
    CSB-YP667608MO
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Ulk4重組蛋白
  • 貨號(hào)：
    CSB-EP667608MO
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Ulk4重組蛋白
  • 貨號(hào)：
    CSB-EP667608MO-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Ulk4重組蛋白
  • 貨號(hào)：
    CSB-BP667608MO
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Ulk4重組蛋白
  • 貨號(hào)：
    CSB-MP667608MO
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Ulk4
  • Uniprot No.：
  • 別名：
    Ulk4; Serine/threonine-protein kinase ULK4; EC 2.7.11.1; Unc-51-like kinase 4
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    May be involved in the remodeling of cytoskeletal components, such as alpha-tubulin, and in this way regulates neurite branching and elongation, as well as cell motility.
  • 基因功能參考文獻(xiàn)：
    1. Ulk4 +/tm1a mice exhibit anxiety-related phenotype. PMID: 29391390
    2. This is the first evidence demonstrating that ULK4 is a crucial regulator of myelination, and ULK4 may therefore become a novel therapeutic target for hypomyelination diseases. PMID: 29034508
    3. Targeted disruption of the Ulk4 perturbed mid-neurogenesis and significantly reduced cerebral cortex in postnatal mice. PMID: 27300315
    4. This study showed that Ulk4 Is essential for Ciliogenesis and CSF Flow in mice PMID: 27445138
    5. Congenital hydrocephalus with suppurative rhinosinusitis and otitis media in Ulk4 null mice indicative of primary ciliary dyskinesis PMID: 21746835

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  • 蛋白家族：
    Protein kinase superfamily, Ser/Thr protein kinase family, APG1/unc-51/ULK1 subfamily
  • 組織特異性：
    Expressed in embryonic and adult brain. In the brain, widely expressed, with highest levels in layers II/III and V of the cortex, piriform cortex, CA1-3 of hippocampus, dentate gyrus, ependymal cells lining the ventricles and choroid plexus, and in the th
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