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  4. Recombinant Nuclear hormone receptor family member nhr-25 (nhr-25), partial

Recombinant Nuclear hormone receptor family member nhr-25 (nhr-25), partial

  • 中文名稱：
    秀麗隱桿線蟲nhr-25重組蛋白
  • 貨號：
    CSB-YP619292CXY
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    秀麗隱桿線蟲nhr-25重組蛋白
  • 貨號：
    CSB-EP619292CXY
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    秀麗隱桿線蟲nhr-25重組蛋白
  • 貨號：
    CSB-EP619292CXY-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    秀麗隱桿線蟲nhr-25重組蛋白
  • 貨號：
    CSB-BP619292CXY
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    秀麗隱桿線蟲nhr-25重組蛋白
  • 貨號：
    CSB-MP619292CXY
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    nhr-25
  • Uniprot No.：
  • 別名：
    nhr-25; F11C1.6; Nuclear hormone receptor family member nhr-25
  • 種屬：
    Caenorhabditis elegans
  • 蛋白長度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Orphan nuclear receptor and probable transcription activator, required during development. Plays a role in male tail tip morphogenesis regulating the expression of the transcription factor dmd-3 in a negative feedback loop. Regulates vulval precursor cell (VPC) differentiation, in concert with homeobox protein lin-39. Involved in promoting embryogenesis, in concert with homeobox protein nob-1.
  • 基因功能參考文獻(xiàn)：
    1. these data indicate that inactivation of either acs-3 or nhr-25 causes stress sensitivity and increased expression of innate immunity/stress genes, most likely by different mechanisms. PMID: 24651852
    2. We conclude that sumoylation operates at multiple levels to affect NHR-25 activity in a highly coordinated spatial and temporal manner PMID: 24348269
    3. Functional validation of a subset of the target genes showed both activating and inhibitory roles of NHR-25 and ELT-3 in regulating their targets. PMID: 24097988
    4. ACS-3-derived long-chain fatty acyl-CoAs, perhaps incorporated into complex ligands such as phosphoinositides, modulate NHR-25 function, which in turn regulates an endocrine program of lipid uptake and synthesis. PMID: 20889131
    5. Results indicate that nhr-25 plays an integral role in regulating cellular processes of epidermal cells. PMID: 15314147
    6. NHR-25 knockdown restores DTC formation and fertility in pop-1 and sys-1 mutants, suggesting that a balance between NHR-25 and beta-catenin pathway activities is required to establish both proximal and distal fates. PMID: 16890160

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  • 亞細(xì)胞定位：
    Nucleus.
  • 蛋白家族：
    Nuclear hormone receptor family
  • 組織特異性：
    Expressed in the epidermis, the developing somatic gonad, and a subset of other epithelial cells.
  • 數(shù)據(jù)庫鏈接：

    KEGG: cel:CELE_F11C1.6

    STRING: 6239.F11C1.6a

    UniGene: Cel.7338