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  4. Recombinant Partitioning defective protein 3 (par-3), partial

Recombinant Partitioning defective protein 3 (par-3), partial

  • 中文名稱(chēng)：
    秀麗隱桿線(xiàn)蟲(chóng)par-3重組蛋白
  • 貨號(hào)：
    CSB-YP622011CXY
  • 規(guī)格：
  • 來(lái)源：
    Yeast
  • 其他：
  • 中文名稱(chēng)：
    秀麗隱桿線(xiàn)蟲(chóng)par-3重組蛋白
  • 貨號(hào)：
    CSB-EP622011CXY
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 其他：
  • 中文名稱(chēng)：
    秀麗隱桿線(xiàn)蟲(chóng)par-3重組蛋白
  • 貨號(hào)：
    CSB-EP622011CXY-B
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱(chēng)：
    秀麗隱桿線(xiàn)蟲(chóng)par-3重組蛋白
  • 貨號(hào)：
    CSB-BP622011CXY
  • 規(guī)格：
  • 來(lái)源：
    Baculovirus
  • 其他：
  • 中文名稱(chēng)：
    秀麗隱桿線(xiàn)蟲(chóng)par-3重組蛋白
  • 貨號(hào)：
    CSB-MP622011CXY
  • 規(guī)格：
  • 來(lái)源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    par-3
  • Uniprot No.：
  • 別名：
    par-3; F54E7.3Partitioning defective protein 3; Abnormal embryonic partitioning of cytoplasm protein 3
  • 種屬：
    Caenorhabditis elegans
  • 蛋白長(zhǎng)度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    In cooperation with pkc-3, required for establishing cell polarity and regulating spindle orientation in the early embryo. Localization is crucial for recruiting par-6 and pkc-3 to the peripheral apical cortex and restricting par-2 to basolateral surfaces. Necessary for apicobasal and anterior-posterior asymmetries associated with cell adhesion and gastrulation during the first few cycles of embryogenesis, and also for epithelial cell polarity in the distal spermatheca. Regulates the asymmetric localization of csnk-1, ppk-1 and gpr-1/2 during the first embryonic division.
  • 基因功能參考文獻(xiàn)：
    1. a model of interactions between the Par proteins that includes both mutual inhibition and PAR-3 oligomerization PMID: 21943422
    2. Different domains of C. elegans par-3 are required at different times in development. PMID: 20678977
    3. PAR-3 foci move apically and cluster, and PAR-3 is required to assemble E-cadherin into foci and for foci to accumulate at the apical surface. PMID: 20431121
    4. PAR-3 activity is required for the proper polarization of spermathecal cells and that defective ovulation results from defective distal spermathecal development. PMID: 15151982
    5. PAR-3 and PAR-1 have graded cortical distributions with the highest levels at the anterior and posterior poles, respectively, and the lowest levels of these proteins correlate with high LET-99 accumulation PMID: 17761536

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  • 亞細(xì)胞定位：
    Cytoplasm. Note=Cytoplasmic and cell periphery.
  • 蛋白家族：
    PAR3 family
  • 組織特異性：
    Asymmetrically distributed at the periphery of the zygote and in dividing blastomeres of the germline lineage. Coexpressed with par-6; patchy expression observed at the periphery after completion of meiosis I and in meiosis II. On completion of metaphase
  • 數(shù)據(jù)庫(kù)鏈接：

    STRING: 6239.F54E7.3b.2

    UniGene: Cel.5328