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  4. Recombinant Rat A disintegrin and metalloproteinase with thrombospondin motifs 7 (Adamts7), partial

Recombinant Rat A disintegrin and metalloproteinase with thrombospondin motifs 7 (Adamts7), partial

  • 中文名稱：
    Recombinant Rat A disintegrin and metalloproteinase with thrombospondin motifs 7(Adamts7) ,partial
  • 貨號：
    CSB-YP626048RA
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Rat A disintegrin and metalloproteinase with thrombospondin motifs 7(Adamts7) ,partial
  • 貨號：
    CSB-EP626048RA
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Rat A disintegrin and metalloproteinase with thrombospondin motifs 7(Adamts7) ,partial
  • 貨號：
    CSB-EP626048RA-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Rat A disintegrin and metalloproteinase with thrombospondin motifs 7(Adamts7) ,partial
  • 貨號：
    CSB-BP626048RA
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Rat A disintegrin and metalloproteinase with thrombospondin motifs 7(Adamts7) ,partial
  • 貨號：
    CSB-MP626048RA
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Adamts7
  • Uniprot No.：
  • 別名：
    Adamts7A disintegrin and metalloproteinase with thrombospondin motifs 7; ADAM-TS 7; ADAM-TS7; ADAMTS-7; EC 3.4.24.-; COMPase
  • 種屬：
    Rattus norvegicus (Rat)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Metalloprotease that may play a role in the degradation of COMP.
  • 基因功能參考文獻：
    1. Study shows that elevated ADAMTS-7 levels may be involved in ventricular remodeling after acute myocardial infarction. PMID: 26938210
    2. data demonstrates that ADAMTS-7 promotes VSMC proliferation both in vitro and in vivo. ADAMTS-7 may therefore serve as a novel therapeutic target for atherosclerosis and post-angioplasty restenosis PMID: 25921940
    3. ADAMTS-7 and TNF-alpha form a positive feedback loop in the regulation of cartilage degradation and osteoarthritis progression. PMID: 23928557
    4. ADAMTS-7 upregulation by miR-29a/b repression mediates vascular calcification, which may shed light on preventing cardiovascular morbidity and mortality. PMID: 22995515
    5. ADAMTS-7 is the first metalloproteinase found to bind directly to and degrade COMP PMID: 16585064
    6. ADAMTS-7 mediates vascular smooth muscle cell migration and neointima formation in balloon-injured rat arteries. PMID: 19168437

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  • 亞細胞定位：
    Secreted, extracellular space, extracellular matrix.
  • 組織特異性：
    Detected in liver, ovary, kidney, testicle, lung and embryo.
  • 數(shù)據(jù)庫鏈接：