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  4. Recombinant Saccharomyces cerevisiae Autophagy-related protein 11 (ATG11), partial

Recombinant Saccharomyces cerevisiae Autophagy-related protein 11 (ATG11), partial

  • 中文名稱(chēng)：
    Recombinant Saccharomyces cerevisiae Autophagy-related protein 11(ATG11) ,partial
  • 貨號(hào)：
    CSB-YP622493SVG
  • 規(guī)格：
  • 來(lái)源：
    Yeast
  • 其他：
  • 中文名稱(chēng)：
    Recombinant Saccharomyces cerevisiae Autophagy-related protein 11(ATG11) ,partial
  • 貨號(hào)：
    CSB-EP622493SVG
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 其他：
  • 中文名稱(chēng)：
    Recombinant Saccharomyces cerevisiae Autophagy-related protein 11(ATG11) ,partial
  • 貨號(hào)：
    CSB-EP622493SVG-B
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱(chēng)：
    Recombinant Saccharomyces cerevisiae Autophagy-related protein 11(ATG11) ,partial
  • 貨號(hào)：
    CSB-BP622493SVG
  • 規(guī)格：
  • 來(lái)源：
    Baculovirus
  • 其他：
  • 中文名稱(chēng)：
    Recombinant Saccharomyces cerevisiae Autophagy-related protein 11(ATG11) ,partial
  • 貨號(hào)：
    CSB-MP622493SVG
  • 規(guī)格：
  • 來(lái)源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    ATG11
  • Uniprot No.：
  • 別名：
    ATG11; CVT9; YPR049C; YP9499.07cAutophagy-related protein 11; Cytoplasm to vacuole targeting protein 9
  • 種屬：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 蛋白長(zhǎng)度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Involved in cytoplasm to vacuole transport (Cvt), pexophagy, mitophagy and nucleophagy. Recruits mitochondria for their selective degradation via autophagy (mitophagy) during starvation, through its interaction with ATG32. Works as scaffold proteins that recruit ATG proteins to the pre-autophagosome (PAS), the site of vesicle/autophagosome formation. Required for ATG9 anterograde transport from the mitochondria to the PAS. Recruits also the ATG19-prAPE1 complex to the PAS. Required for the Cvt vesicles completion. Plays a significant role in life span extension.
  • 基因功能參考文獻(xiàn)：
    1. Atg11 plays important roles in low-level nonselective autophagy PMID: 28013049
    2. Atg29 phosphorylation regulates coordination of the Atg17-Atg31-Atg29 complex with the Atg11 scaffold during autophagy initiation. PMID: 23858448
    3. When mitophagy is induced, Atg11 in turn attracts other mitochondrial fission proteins and promotes mitochondrial division. PMID: 23810512
    4. findings suggest that Atg11 plays an integral role in connecting cargo molecules with components of the vesicle-forming machinery PMID: 15659643
    5. Atg11 connecs cargoes, actin and pre-utophagosomal structure (PAS) elements. PMID: 16874092
    6. ATG11 is essential for selective autophagy and mitophagy PMID: 18818209

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  • 亞細(xì)胞定位：
    Preautophagosomal structure membrane; Peripheral membrane protein. Vacuole membrane; Peripheral membrane protein. Note=During pexophagy, accumulates in the vacuolar membrane region, where the peroxisomes contact the vacuole. ATG11 localization is dependent on ATG11-ATG30 interaction.
  • 蛋白家族：
    ATG11 family
  • 數(shù)據(jù)庫(kù)鏈接：

    KEGG: sce:YPR049C

    STRING: 4932.YPR049C