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  4. Recombinant Saccharomyces cerevisiae Lanosterol 14-alpha demethylase (ERG11), partial

Recombinant Saccharomyces cerevisiae Lanosterol 14-alpha demethylase (ERG11), partial

In Stock
  • 中文名稱：
    釀酒酵母ERG11重組蛋白
  • 貨號：
    CSB-EP006459SVG1
  • 規(guī)格：
    ￥2328
  • 圖片：
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他：

產品詳情

  • 純度：
    Greater than 90% as determined by SDS-PAGE.
  • 基因名：
    ERG11
  • Uniprot No.：
  • 別名：
    ERG11; CYP51; YHR007CLanosterol 14-alpha demethylase; EC 1.14.14.154; CYPLI; Cytochrome P450 51; Cytochrome P450-14DM; Cytochrome P450-LIA1; Sterol 14-alpha demethylase
  • 種屬：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 蛋白長度：
    Extracellular Domain
  • 來源：
    E.coli
  • 分子量：
    29.1kDa
  • 表達區(qū)域：
    1-20aa
  • 氨基酸序列
    MSATKSIVGEALEYVNIGLS
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽：
    N-terminal GST-tagged
  • 產品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液：
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    3-7 business days
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Catalyzes C14-demethylation of lanosterol which is critical for ergosterol biosynthesis. It transforms lanosterol into 4,4'-dimethyl cholesta-8,14,24-triene-3-beta-ol.
  • 基因功能參考文獻：
    1. molecular characterization of Erg11 including interactions with NADPH-cytochrome P450 reductase and role of Erg11 in antifungal resistance [REVIEW] PMID: 22217856
  • 亞細胞定位：
    Membrane; Single-pass membrane protein.
  • 蛋白家族：
    Cytochrome P450 family
  • 數(shù)據庫鏈接：

    KEGG: sce:YHR007C

    STRING: 4932.YHR007C