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  4. Recombinant Saccharomyces cerevisiae Mitochondrial import inner membrane translocase subunit TIM17 (TIM17), partial

Recombinant Saccharomyces cerevisiae Mitochondrial import inner membrane translocase subunit TIM17 (TIM17), partial

  • 中文名稱：
    釀酒酵母TIM17重組蛋白
  • 貨號(hào)：
    CSB-YP331035SVG1
  • 規(guī)格：
  • 來(lái)源：
    Yeast
  • 其他：
  • 中文名稱：
    釀酒酵母TIM17重組蛋白
  • 貨號(hào)：
    CSB-EP331035SVG1
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 其他：
  • 中文名稱：
    釀酒酵母TIM17重組蛋白
  • 貨號(hào)：
    CSB-EP331035SVG1-B
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    釀酒酵母TIM17重組蛋白
  • 貨號(hào)：
    CSB-BP331035SVG1
  • 規(guī)格：
  • 來(lái)源：
    Baculovirus
  • 其他：
  • 中文名稱：
    釀酒酵母TIM17重組蛋白
  • 貨號(hào)：
    CSB-MP331035SVG1
  • 規(guī)格：
  • 來(lái)源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    TIM17
  • Uniprot No.：
  • 別名：
    TIM17; MIM17; MPI2; SMS1; YJL143W; J0648; Mitochondrial import inner membrane translocase subunit TIM17; Mitochondrial inner membrane protein MIM17; Mitochondrial protein import protein 2
  • 種屬：
    Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
  • 蛋白長(zhǎng)度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane.
  • 基因功能參考文獻(xiàn)：
    1. Mutations in TM1 and TM2 impaired the interaction of Tim17 with Tim23, component of the translocation channel, whereas mutations in TM3 compromised binding of the import motor. The authors identified residues in the matrix-facing region of Tim17 involved in binding of the import motor. PMID: 28165323
    2. charged residues in Tim17 are critical for the preprotein-induced gating of the TIM23 translocase PMID: 15618217
    3. Tim17p is required for twin pore structure and provides the voltage gate for the TIM23 channel complex. PMID: 17148445
    4. Overexpression of TIM17 prevents the complete loss of mtDNA in cells lacking Abf2. PMID: 18826960
  • 亞細(xì)胞定位：
    Mitochondrion inner membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Tim17/Tim22/Tim23 family
  • 數(shù)據(jù)庫(kù)鏈接：

    KEGG: sce:YJL143W

    STRING: 4932.YJL143W