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  4. Recombinant Arabidopsis thaliana Bax inhibitor 1 (BI-1)

Recombinant Arabidopsis thaliana Bax inhibitor 1 (BI-1)

  • 中文名稱：
    Recombinant Arabidopsis thaliana Bax inhibitor 1(BI-1)
  • 貨號(hào)：
    CSB-CF873243DOA
  • 規(guī)格：
  • 來源：
    in vitro E.coli expression system
  • 其他：

產(chǎn)品詳情

  • 基因名：
    BI-1
  • Uniprot No.：
  • 別名：
    BI-1; At5g47120; K14A3.7; Bax inhibitor 1; AtBI-1; BI-1
  • 種屬：
    Arabidopsis thaliana (Mouse-ear cress)
  • 蛋白長(zhǎng)度：
    full length protein
  • 表達(dá)區(qū)域：
    1-247
  • 氨基酸序列
    MDAFSSFFDSQPGSRSWSYDSLKNFRQISPAVQNHLKRVYLTLCCALVASAFGAYLHVLW NIGGILTTIGCIGTMIWLLSCPPYEHQKRLSLLFVSAVLEGASVGPLIKVAIDVDPSILI TAFVGTAIAFVCFSAAAMLARRREYLYLGGLLSSGLSMLMWLQFASSIFGGSASIFKFEL YFGLLIFVGYMVVDTQEIIEKAHLGDMDYVKHSLTLFTDFVAVFVRILIIMLKNSADKEE KKKKRRN
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽：
    N-terminal 10xHis-tagged
  • 產(chǎn)品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液：
    Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Suppressor of apoptosis. Modulator of endoplasmic reticulum stress-mediated programmed cell death. Involved in methyl jasmonate-induced leaf senescence through regulating cytoplasmic calcium level.
  • 基因功能參考文獻(xiàn)：
    1. BI-1 affects cell death-associated components localized in sphingolipid-enriched microdomains of the plasma membrane. PMID: 26297139
    2. AtBI-1 contributes to synthesis of sphingolipids during cold stress by interacting with AtSLD1, AtFAH1, AtSBH2 and AtADS2. PMID: 24687220
    3. Arabidopsis thaliana BI-1-interacting proteins were identified. PMID: 23782494
    4. Overexpression of AtBI-1 increases the amount of 2-hydroxy fatty acids. PMID: 19054355
    5. BAX INHIBITOR 1 is an attenuator for cell death progression triggered by both biotic and abiotic types of cell death signals in Arabidopsis. PMID: 16507080
    6. The expression of AtBI-1, which suppresses Bax-induced cell death, in the tapetum at the tetrad stage inhibits tapetum degeneration and subsequently results in pollen abortion, while activation of AtBI-1 at the later stage does not. PMID: 16565524
    7. A study evaluating the effect of AtBI-1 on calcium homeostasis is reported. PMID: 17142482
    8. BI-1 requires normal electron transport activity to suppress cell death in yeast PMID: 17825821
    9. Results indicate that the loss of calmodulin binding reduces the cell death suppressor activity of Bax inhibitor-1 in planta. PMID: 19674971

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  • 亞細(xì)胞定位：
    Endoplasmic reticulum membrane; Multi-pass membrane protein.
  • 蛋白家族：
    BI1 family
  • 組織特異性：
    Expressed in root tips, root vasculature, flower tissues, including stamens and sepals, and in the base of siliques. Not detected in mature leaves.
  • 數(shù)據(jù)庫(kù)鏈接：

    KEGG: ath:AT5G47120

    STRING: 3702.AT5G47120.1

    UniGene: At.24669