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  4. Recombinant Human Membrane-spanning 4-domains subfamily A member 4A (MS4A4A)-VLPs

Recombinant Human Membrane-spanning 4-domains subfamily A member 4A (MS4A4A)-VLPs

  • 中文名稱：
    Recombinant Human Membrane-spanning 4-domains subfamily A member 4A (MS4A4A)-VLPs
  • 貨號：
    CSB-MP822238HU
  • 規(guī)格：
    ￥5250
  • 圖片：
    • The purity of VLPs was greater than 95% as determined by SEC-HPLC
    • CSB-MP822238HU is detected by Mouse anti-6*His monoclonal antibody.
  • 其他：

產(chǎn)品詳情

  • 純度：
    Greater than 95% as determined by SEC-HPLC.
  • 基因名：
  • Uniprot No.：
  • 別名：
    CD20 antigen-like 1;Four-span transmembrane protein 1
  • 種屬：
    Homo sapiens (Human)
  • 蛋白長度：
    Full Length
  • 來源：
    Mammalian cell
  • 表達(dá)區(qū)域：
    1-239aa
  • 氨基酸序列
    MHQTYSRHCRPEESTFSAAMTTMQGMEQAMPGAGPGVPQLGNMAVIHSHLWKGLQEKFLKGEPKVLGVVQILTALMSLSMGITMMCMASNTYGSNPISVYIGYTIWGSVMFIISGSLSIAAGIRTTKGLVRGSLGMNITSSVLAASGILINTFSLAFYSFHHPYCNYYGNSNNCHGTMSILMGLDGMVLLLSVLEFCIAVSLSAFGCKVLCCTPGGVVLILPSHSHMAETASPTPLNEV
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽：
    C-terminal 10xHis-tagged
    If you have specified tag type, please tell us and we will check if it's possible to develop.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液：
    Lyophilized from PBS, 6% Trehalose, pH 7.4.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein indeionized sterile water to a concentration of 0.1-1.0 mg/mL.Aliquot for long-term storage at -80℃. Solubilize for 60 minutes at room temperature with occasional gentle mixing. Avoid vigorous shaking or vortexing.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 注意事項(xiàng)：
    The VLPs are expressed from human 293 cells (HEK293).Mix the sample gently by repeatedly pipetting it up and down. Do not vortex. Repeated freezing and thawing is not recommended.Store the protein at -20℃/-80℃ upon receiving it, and ensure to avoid repeated freezing and thawing, otherwise, it will affect the protein activity. The immunization strategy should be optimized (antigen dose, regimen and adjuvant).
  • Datasheet & COA：
    Please contact us to get it.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能：
    May be involved in signal transduction as a component of a multimeric receptor complex.
  • 基因功能參考文獻(xiàn)：
    1. MS4A4A is expressed at the plasma membrane in monocytes but not in granulocytes or lymphocytes. PMID: 28303902
    2. MS4A4A expression is significantly upregulated in human masticatory mucosa during wound healing PMID: 28005267
    3. MS4A4 in human mast cells effects ligand-induced KIT endocytosis pathways and reduced receptor recycling to the cell surface, thus promoting KIT signaling in the endosomes while reducing that in the plasma membrane. PMID: 25717186
    4. Single nucleotide polymorphisms in APOE-epsilon4, CLU and MS4A4A influence both Alzheimer disease risk and cerebrospinal fluid Amyloid-beta1-42 levels. PMID: 23573206
  • 亞細(xì)胞定位：
    Membrane; Multi-pass membrane protein.
  • 蛋白家族：
    MS4A family
  • 組織特異性：
    Variable expression in multiple hemopoietic cell lines.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 13371

    OMIM: 606547

    KEGG: hsa:51338

    STRING: 9606.ENSP00000338648

    UniGene: Hs.325960