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  4. MS4A4A Antibody, FITC conjugated

MS4A4A Antibody, FITC conjugated

  • 中文名稱：
    MS4A4A兔多克隆抗體, FITC偶聯(lián)
  • 貨號：
    CSB-PA822238LC01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) MS4A4A Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    MS4A4A; 4SPAN1; CD20L1; MS4A4; HDCME31P; Membrane-spanning 4-domains subfamily A member 4A; CD20 antigen-like 1; Four-span transmembrane protein 1
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Membrane-spanning 4-domains subfamily A member 4A protein (1-64AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

  • 功能：
    May be involved in signal transduction as a component of a multimeric receptor complex.
  • 基因功能參考文獻(xiàn)：
    1. MS4A4A is expressed at the plasma membrane in monocytes but not in granulocytes or lymphocytes. PMID: 28303902
    2. MS4A4A expression is significantly upregulated in human masticatory mucosa during wound healing PMID: 28005267
    3. MS4A4 in human mast cells effects ligand-induced KIT endocytosis pathways and reduced receptor recycling to the cell surface, thus promoting KIT signaling in the endosomes while reducing that in the plasma membrane. PMID: 25717186
    4. Single nucleotide polymorphisms in APOE-epsilon4, CLU and MS4A4A influence both Alzheimer disease risk and cerebrospinal fluid Amyloid-beta1-42 levels. PMID: 23573206
  • 亞細(xì)胞定位：
    Membrane; Multi-pass membrane protein.
  • 蛋白家族：
    MS4A family
  • 組織特異性：
    Variable expression in multiple hemopoietic cell lines.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 13371

    OMIM: 606547

    KEGG: hsa:51338

    STRING: 9606.ENSP00000338648

    UniGene: Hs.325960