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ACE

ACE,即血管緊張素轉(zhuǎn)換酶,別名CD143、DCP1、MVCD3。它是一種關(guān)鍵的肽基肽酶,由ACE基因編碼,廣泛分布于肺、腎臟和血管內(nèi)皮細(xì)胞。它通過(guò)將無(wú)活性的血管緊張素I轉(zhuǎn)化為有活性的血管緊張素II,調(diào)節(jié)血管的收縮與舒張,進(jìn)而影響血壓和體內(nèi)水分平衡。ACE還參與激活凝血酶原,促進(jìn)血液凝固。在生物學(xué)上,ACE對(duì)維持心血管健康和體液電解質(zhì)平衡至關(guān)重要,其活性異常與高血壓、心血管疾病等密切相關(guān)。ACE抑制劑是治療高血壓和心力衰竭等病癥的常用藥物,通過(guò)降低血管緊張素II水平,減輕心臟負(fù)擔(dān),保護(hù)心血管系統(tǒng)。

熱銷產(chǎn)品

ACE Recombinant Monoclonal Antibody (CSB-RA268157A0HU)

驗(yàn)證數(shù)據(jù)

CSB-RA268157A0HU

IHC image of CSB-RA268157A0HU diluted at 1:100 and staining in paraffin-embedded human lung tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

CSB-RA268157A0HU

IHC image of CSB-RA268157A0HU diluted at 1:100 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

ACE Antibodies

ACE for Homo sapiens (Human)

ACE for Rattus norvegicus (Rat)

ACE Proteins

ACE Proteins for Homo sapiens (Human)

ACE Proteins for Bos taurus (Bovine)

ACE Proteins for Oryctolagus cuniculus (Rabbit)

ACE Proteins for Mus musculus (Mouse)

ACE Proteins for Rattus norvegicus (Rat)

ACE Proteins for Drosophila melanogaster (Fruit fly)

ACE Proteins for Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

ACE Proteins for Haematobia irritans exigua (Buffalo fly)

ACE Proteins for Gallus gallus (Chicken)

ACE Proteins for Mesocricetus auratus (Golden hamster)

ACE Proteins for Theromyzon tessulatum (Duck leech)

ACE Proteins for Anopheles gambiae (African malaria mosquito)

ACE Proteins for Pan troglodytes (Chimpanzee)

ACE ELISA Kit

ACE ELISA Kit for Homo sapiens (Human)

ACE ELISA Kit for Mus musculus (Mouse)

ACE ELISA Kit for Rattus norvegicus (Rat)