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APOH

APOH,全稱為beta-2-glycoprotein I,也被稱為載脂蛋白H。該蛋白由APOH基因編碼,主要由肝細(xì)胞合成,屬于糖蛋白。APOH蛋白具有多種別名,包括BG、B2G1等。APOH蛋白在人體中發(fā)揮著多種生理功能,如結(jié)合磷脂、肝素、磷脂和硫酸葡聚糖等帶負(fù)電荷的物質(zhì)。它參與凝血過程,可改變ADP介導(dǎo)的血小板凝集,通過與受損細(xì)胞表面的磷脂結(jié)合,阻止先天性凝血級聯(lián)的激活,表現(xiàn)出抗凝血活性。APOH蛋白的血漿濃度與代謝綜合征的改變和2型糖尿病的血管病變密切相關(guān),被用作評估心血管風(fēng)險(xiǎn)的臨床指標(biāo)。此外,APOH蛋白還與抗磷脂綜合征、肝梗死等疾病相關(guān)。目前,針對APOH蛋白的藥物研發(fā)正在積極進(jìn)行中,例如用于治療抗磷脂綜合征的檢測試劑盒和用于研究肝梗死的動(dòng)物模型等。

熱銷產(chǎn)品

Recombinant Human Beta-2-glycoprotein 1 (APOH), partial (CSB-EP001939HU1)

驗(yàn)證數(shù)據(jù)

CSB-EP001939HU1

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

APOH Antibody (CSB-PA11079A0Rb)

驗(yàn)證數(shù)據(jù)

CSB-PA11079A0Rb

Western Blot
Positive WB detected in: Rat liver tissue
All lanes: APOH antibody at 3.2μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 39 kDa
Observed band size: 39 kDa

CSB-PA11079A0Rb

Immunohistochemistry of paraffin-embedded human liver cancer using CSB-PA11079A0Rb at dilution of 1:100

CSB-PA11079A0Rb

Immunofluorescent analysis of HepG2 cells using CSB-PA11079A0Rb at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

Human Apolipoprotein H(APOH) ELISA kit (CSB-E08961h)

驗(yàn)證數(shù)據(jù)

CSB-E08961h 標(biāo)準(zhǔn)曲線

貨號(hào):CSB-E08961h

規(guī)格:96T/48T

靈敏度:3.9 ng/mL

檢測范圍:15.6 ng/mL-1000 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

APOH Antibodies

APOH for Homo sapiens (Human)

APOH Proteins

APOH Proteins for Bos taurus (Bovine)

APOH Proteins for Rattus norvegicus (Rat)

APOH Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

APOH Proteins for Homo sapiens (Human)

APOH Proteins for Pan troglodytes (Chimpanzee)

APOH ELISA Kit

APOH ELISA Kit for Mus musculus (Mouse)

APOH ELISA Kit for Rattus norvegicus (Rat)

APOH ELISA Kit for Homo sapiens (Human)