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CCL17

CCL17,即C-C基序趨化因子配體17,別名A152E53、ABCD2、C-C motif chemokine 17。它是一種小分子肽,屬于CC型趨化因子,主要通過與其膜受體CCR4結(jié)合發(fā)揮生物學(xué)功能。CCL17在多種T淋巴細(xì)胞亞群的細(xì)胞膜表面表達(dá),尤其在輔助性T細(xì)胞上表達(dá)較高。它具有多樣的生物學(xué)功能,參與炎癥、超敏反應(yīng)、自身免疫性疾病以及腫瘤微環(huán)境的調(diào)節(jié)。研究發(fā)現(xiàn)CCL17可能通過調(diào)節(jié)性T細(xì)胞(Treg)促進(jìn)腫瘤生長與轉(zhuǎn)移,但在特定條件下也可能具有抗腫瘤免疫作用。此外,CCL17在心血管老化中的作用也受到關(guān)注,其抑制可能成為治療心血管老化的潛在策略。

熱銷產(chǎn)品

CCL17 Antibody (CSB-PA856406LA01HU)

驗證數(shù)據(jù)

CSB-PA856406LA01HU

Immunohistochemistry of paraffin-embedded human glioma using CSB-PA856406LA01HU at dilution of 1:100

CSB-PA856406LA01HU

Immunohistochemistry of paraffin-embedded human cervical cancer using CSB-PA856406LA01HU at dilution of 1:100

CCL17 Antibodies

CCL17 for Homo sapiens (Human)

CCL17 Proteins

CCL17 Proteins for Macaca mulatta (Rhesus macaque)

CCL17 Proteins for Felis catus (Cat) (Felis silvestris catus)

CCL17 Proteins for Homo sapiens (Human)

CCL17 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

CCL17 ELISA Kit

CCL17 ELISA Kit for Homo sapiens (Human)

CCL17 ELISA Kit for Monkey

CCL17 ELISA Kit for Canis lupus familiaris (Dog) (Canis familiaris)