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CCL28

CCL28,也稱為粘膜相關(guān)上皮趨化因子(MEC),是一種參與粘膜免疫的細(xì)胞因子。它最初在粘膜組織中被發(fā)現(xiàn),與IgA抗體的分泌有關(guān)。CCL28可以與CCR3和CCR10受體結(jié)合,介導(dǎo)免疫反應(yīng)和病毒感染。CCL28在多種粘膜部位表達(dá),包括唾液腺、乳腺、氣管和結(jié)腸等。它還在人類的脾臟和肺中有表達(dá)。研究表明,CCL28在類風(fēng)濕關(guān)節(jié)炎、炎癥性腸病和潰瘍性結(jié)腸炎等炎癥性疾病中表達(dá)上調(diào)。此外,CCL28也在乳腺癌中高表達(dá)。目前,針對(duì)CCL28的藥物研發(fā)主要集中在抑制其與受體的結(jié)合或調(diào)節(jié)其表達(dá),以治療炎癥性疾病和腫瘤。

熱銷產(chǎn)品

CCL28 Antibody (CSB-PA868302ESR1HU)

驗(yàn)證數(shù)據(jù)

CSB-PA868302ESR1HU

Western blot
All lanes: C-C motif chemokine 28 antibody at 5μg/ml + Mouse spleen tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 15, 13 kDa
Observed band size: 15 kDa

CSB-PA868302ESR1HU

Immunohistochemistry of paraffin-embedded human salivary gland tissue using CSB-PA868302ESR1HU at dilution of 1:100

CSB-PA868302ESR1HU

Immunohistochemistry of paraffin-embedded human colon tissue using CSB-PA868302ESR1HU at dilution of 1:100

CSB-PA868302ESR1HU

Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA868302ESR1HU at dilution of 1:100

Human mucosae associated epithelia chemokine,MEC ELISA Kit (CSB-E07310h)

驗(yàn)證數(shù)據(jù)

CSB-E07310h 標(biāo)準(zhǔn)曲線

貨號(hào):CSB-E07310h

規(guī)格:96T/48T

靈敏度:19.5 pg/ml

檢測(cè)范圍:78 pg/ml - 5000 pg/ml

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

CCL28 Antibodies

CCL28 for Homo sapiens (Human)

CCL28 Proteins

CCL28 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

CCL28 Proteins for Mus musculus (Mouse)

CCL28 Proteins for Homo sapiens (Human)

CCL28 ELISA Kit

CCL28 ELISA Kit for Homo sapiens (Human)

CCL28 ELISA Kit for Mus musculus (Mouse)