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CNOT9

Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Involved in down-regulation of MYB- and JUN-dependent transcription. May play a role in cell differentiation (By similarity). Can bind oligonucleotides, such as poly-G, poly-C or poly-T (in vitro), but the physiological relevance of this is not certain. Does not bind poly-A. Enhances ligand-dependent transcriptional activity of nuclear hormone receptors, including RARA, expect ESR1-mediated transcription that is not only slightly increased, if at all.

CNOT9 Antibodies

CNOT9 for Homo sapiens (Human)

CNOT9 Proteins

CNOT9 Proteins for Bos taurus (Bovine)

CNOT9 Proteins for Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

CNOT9 Proteins for Rattus norvegicus (Rat)

CNOT9 Proteins for Pongo abelii (Sumatran orangutan)

CNOT9 Proteins for Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)

CNOT9 Proteins for Xenopus laevis (African clawed frog)

CNOT9 Proteins for Danio rerio (Zebrafish) (Brachydanio rerio)

CNOT9 Proteins for Homo sapiens (Human)

CNOT9 Proteins for Mus musculus (Mouse)